Effect of Succinate-Containing Infusion Solution
on Cellular Structures in Children in the Perioperative Period

Objective: to evaluate the effect of a 1.5% crystalloid polyionic Reamberin solution on cellular structures in children in the perioperative period. Subjects and methods. A randomized prospective study was conducted in 117 children aged 1 to 18 years during different surgical interventions under ane...

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Bibliographic Details
Main Authors: V. V. Lazarev, K. R. Ermolaeva, V. S. Kochkin, L. E. Tsypin, T. G. Popova, D. V. Nikolaev, A. A. Bologov, N. N. Vaganov
Format: Article
Language:English
Published: Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia 2015-02-01
Series:Общая реаниматология
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Online Access:https://www.reanimatology.com/rmt/article/view/1444
Description
Summary:Objective: to evaluate the effect of a 1.5% crystalloid polyionic Reamberin solution on cellular structures in children in the perioperative period. Subjects and methods. A randomized prospective study was conducted in 117 children aged 1 to 18 years during different surgical interventions under anesthesia with sevoflurane, fentanyl, or rocuronium to provide ASA I—II estimates. A study group included 55 children, in whom basic infusion therapy was switched to infusions of 1.5% Reamberin solution 20 minutes before the end of a surgical intervention. A comparison group comprised 62 children, in whom basic infusion therapy was switched to infusions of 0.9% NaCl solution 20 minutes before the end of surgery. In the study and control groups, the solutions were administered in a dose of 6—10 ml/kg depending on age at a rate of 2 ml/min. Results. 1.5% Reamberin solution was found to contribute to earlier and significant improvement in the function of cellular structures in children in the perioperative period.
ISSN:1813-9779
2411-7110