Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis
PURPOSEThe current meta-analysis aimed to compare the diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) with 18F-FDG PET/magnetic resonance imaging (MRI) in non-small cell lung cancer (NSCLC) lymph node metastasis staging.METHODSWe sea...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Galenos Publishing House
2024-03-01
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| Series: | Diagnostic and Interventional Radiology |
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http://www.dirjournal.org/archives/archive-detail/article-preview/head-to-head-comparison-of-sup18-supf-fdg-pet-ct-a/64365
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| _version_ | 1797268921542246400 |
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| author | Min Zhang Zhikang Liu Yuhang Yuan Wenwen Yang Xiong Cao Minjie Ma Biao Han |
| author_facet | Min Zhang Zhikang Liu Yuhang Yuan Wenwen Yang Xiong Cao Minjie Ma Biao Han |
| author_sort | Min Zhang |
| collection | DOAJ |
| description | PURPOSEThe current meta-analysis aimed to compare the diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) with 18F-FDG PET/magnetic resonance imaging (MRI) in non-small cell lung cancer (NSCLC) lymph node metastasis staging.METHODSWe searched the PubMed, Web of Science, and Embase databases for relevant articles between November 1992 and September 2022. Studies evaluating the head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis in patients with NSCLC were included. The quality of each study was assessed using the Quality Assessment of Diagnostic Performance Studies-2 tool.RESULTSThe analysis includes six studies with a total of 434 patients. The pooled sensitivity of 18F-FDG PET/CT and 18F-FDG PET/MRI was 0.78 [95% confidence interval (CI): 0.59-0.90] and 0.84 (95% CI: 0.68-0.93), and the pooled specificity was 0.87 (95% CI: 0.72-0.94) and 0.87 (95% CI: 0.80-0.92), respectively. The accuracy of 18F-FDG PET/CT and 18F-FDG PET/MRI was 0.81 (95% CI: 0.71-0.90) and 0.84 (95% CI: 0.75-0.92), respectively. When the pre-test probability was set at 50%, the post-test probability for 18F-FDG PET/CT could increase to 85%, and the post-test probability for 18F-FDG PET/MRI could increase to 87%.CONCLUSION18F-FDG PET/CT and 18F-FDG PET/MRI have similar diagnostic performance in detecting lymph node metastasis in NSCLC. However, the results of this study were from a small sample study, and further studies with larger sample sizes are needed. |
| first_indexed | 2024-04-25T01:40:10Z |
| format | Article |
| id | doaj.art-952fde9d261c4ec7bf430a8c8d44d7b5 |
| institution | Directory Open Access Journal |
| issn | 1305-3825 1305-3612 |
| language | English |
| last_indexed | 2024-04-25T01:40:10Z |
| publishDate | 2024-03-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Diagnostic and Interventional Radiology |
| spelling | doaj.art-952fde9d261c4ec7bf430a8c8d44d7b52024-03-08T07:38:32ZengGalenos Publishing HouseDiagnostic and Interventional Radiology1305-38251305-36122024-03-013029910610.4274/dir.2023.23228013049054Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysisMin Zhang0Zhikang Liu1Yuhang Yuan2Wenwen Yang3Xiong Cao4Minjie Ma5Biao Han6 Lanzhou University, The First Clinical Medical College, Lanzhou, China Lanzhou University, The First Clinical Medical College, Lanzhou, China Lanzhou University, The First Clinical Medical College, Lanzhou, China Lanzhou University, The First Clinical Medical College, Lanzhou, China The First Hospital of Lanzhou University, Department of Thoracic Surgery, Lanzhou, China The First Hospital of Lanzhou University, Department of Thoracic Surgery, Lanzhou, China The First Hospital of Lanzhou University, Department of Thoracic Surgery, Lanzhou, China PURPOSEThe current meta-analysis aimed to compare the diagnostic performance of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) with 18F-FDG PET/magnetic resonance imaging (MRI) in non-small cell lung cancer (NSCLC) lymph node metastasis staging.METHODSWe searched the PubMed, Web of Science, and Embase databases for relevant articles between November 1992 and September 2022. Studies evaluating the head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis in patients with NSCLC were included. The quality of each study was assessed using the Quality Assessment of Diagnostic Performance Studies-2 tool.RESULTSThe analysis includes six studies with a total of 434 patients. The pooled sensitivity of 18F-FDG PET/CT and 18F-FDG PET/MRI was 0.78 [95% confidence interval (CI): 0.59-0.90] and 0.84 (95% CI: 0.68-0.93), and the pooled specificity was 0.87 (95% CI: 0.72-0.94) and 0.87 (95% CI: 0.80-0.92), respectively. The accuracy of 18F-FDG PET/CT and 18F-FDG PET/MRI was 0.81 (95% CI: 0.71-0.90) and 0.84 (95% CI: 0.75-0.92), respectively. When the pre-test probability was set at 50%, the post-test probability for 18F-FDG PET/CT could increase to 85%, and the post-test probability for 18F-FDG PET/MRI could increase to 87%.CONCLUSION18F-FDG PET/CT and 18F-FDG PET/MRI have similar diagnostic performance in detecting lymph node metastasis in NSCLC. However, the results of this study were from a small sample study, and further studies with larger sample sizes are needed. http://www.dirjournal.org/archives/archive-detail/article-preview/head-to-head-comparison-of-sup18-supf-fdg-pet-ct-a/64365 18f-fdg pet/ct18f-fdg pet/mrilymph node metastasisnon-small cell lung cancermeta-analysis |
| spellingShingle | Min Zhang Zhikang Liu Yuhang Yuan Wenwen Yang Xiong Cao Minjie Ma Biao Han Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis Diagnostic and Interventional Radiology 18f-fdg pet/ct 18f-fdg pet/mri lymph node metastasis non-small cell lung cancer meta-analysis |
| title | Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis |
| title_full | Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis |
| title_fullStr | Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis |
| title_full_unstemmed | Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis |
| title_short | Head-to-head comparison of 18F-FDG PET/CT and 18F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis |
| title_sort | head to head comparison of 18f fdg pet ct and 18f fdg pet mri for lymph node metastasis staging in non small cell lung cancer a meta analysis |
| topic | 18f-fdg pet/ct 18f-fdg pet/mri lymph node metastasis non-small cell lung cancer meta-analysis |
| url |
http://www.dirjournal.org/archives/archive-detail/article-preview/head-to-head-comparison-of-sup18-supf-fdg-pet-ct-a/64365
|
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