Regulation of autophagy fires up the cold tumor microenvironment to improve cancer immunotherapy

Regulation of autophagy fires up the cold tumor microenvironment to improve cancer immunotherapy

Immunotherapies, such as immune checkpoint inhibitors (ICIs) and chimeric antigen receptor (CAR) T cells, have revolutionized the treatment of patients with advanced and metastatic tumors resistant to traditional therapies. However, the immunosuppressed tumor microenvironment (TME) results in a weak...

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Bibliographic Details
Main Authors: Zhicheng Jin, Xuefeng Sun, Yaoyao Wang, Chao Zhou, Haihua Yang, Suna Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
autophagy
tumor microenvironment
immune cells
immunogenic cell death
antigen presentation
immunotherapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1018903/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.1018903/full

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