EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS
The aim of this study was to know the clinical and haematological changes in female rabbits following the treatment with cypermethrin (CY). In this study, 24 female rabbits were divided randomly into four equal groups A, B, C and D. Groups A, B and C were injected intraperitoneally CY @ 25, 50 and...
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| Format: | Article |
| Language: | English |
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University of Agriculture, Faisalabad
2007-10-01
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| Series: | Pakistan Veterinary Journal |
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| Online Access: | http://pvj.com.pk/pdf-files/27_4/171-175.pdf |
| _version_ | 1819275246460469248 |
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| author | M. KAMAL SHAH, A. KHAN, F. RIZVI, M. SIDDIQUE1 AND SADEEQ-UR-REHMAN2 |
| author_facet | M. KAMAL SHAH, A. KHAN, F. RIZVI, M. SIDDIQUE1 AND SADEEQ-UR-REHMAN2 |
| author_sort | M. KAMAL SHAH, A. KHAN, F. RIZVI, M. SIDDIQUE1 AND SADEEQ-UR-REHMAN2 |
| collection | DOAJ |
| description | The aim of this study was to know the clinical and haematological changes in female rabbits following the treatment with cypermethrin (CY). In this study, 24 female rabbits were divided randomly into four equal groups A, B, C and D. Groups A, B and C were injected intraperitoneally CY @ 25, 50 and 75 mg/Kg b. wt., respectively, while the group D served as control and received normal saline. Rabbits in each group received four treatments at an interval of five days. Blood samples with EDTA were collected after two days of each treatment for haematological studies. All the animals were monitored twice daily for clinical signs. Signs like increased urination, licking of legs, jerky movements, ataxia, incoordination, staggering gait and dizziness persisted for 30 to 90 minutes after each dose. Data analysis revealed that CY affected the haematological parameters in dose dependent manner. There was significant (P<0.05) decrease in RBC counts, Hb concentration and PCV in treated animals indicating that rabbits were suffering from anaemia. There was significant (P<0.05) increase in TLC, lymphocytes and MCV in all treated groups. On the basis of these results, it was concluded that CY is not safe for animals in high doses. |
| first_indexed | 2024-12-23T23:21:17Z |
| format | Article |
| id | doaj.art-953273c6ccb549e3908dfcda1e99145c |
| institution | Directory Open Access Journal |
| issn | 0253-8318 |
| language | English |
| last_indexed | 2024-12-23T23:21:17Z |
| publishDate | 2007-10-01 |
| publisher | University of Agriculture, Faisalabad |
| record_format | Article |
| series | Pakistan Veterinary Journal |
| spelling | doaj.art-953273c6ccb549e3908dfcda1e99145c2022-12-21T17:26:19ZengUniversity of Agriculture, FaisalabadPakistan Veterinary Journal0253-83182007-10-01274171175EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITSM. KAMAL SHAH, A. KHAN, F. RIZVI, M. SIDDIQUE1 AND SADEEQ-UR-REHMAN2The aim of this study was to know the clinical and haematological changes in female rabbits following the treatment with cypermethrin (CY). In this study, 24 female rabbits were divided randomly into four equal groups A, B, C and D. Groups A, B and C were injected intraperitoneally CY @ 25, 50 and 75 mg/Kg b. wt., respectively, while the group D served as control and received normal saline. Rabbits in each group received four treatments at an interval of five days. Blood samples with EDTA were collected after two days of each treatment for haematological studies. All the animals were monitored twice daily for clinical signs. Signs like increased urination, licking of legs, jerky movements, ataxia, incoordination, staggering gait and dizziness persisted for 30 to 90 minutes after each dose. Data analysis revealed that CY affected the haematological parameters in dose dependent manner. There was significant (P<0.05) decrease in RBC counts, Hb concentration and PCV in treated animals indicating that rabbits were suffering from anaemia. There was significant (P<0.05) increase in TLC, lymphocytes and MCV in all treated groups. On the basis of these results, it was concluded that CY is not safe for animals in high doses.http://pvj.com.pk/pdf-files/27_4/171-175.pdfRabbitscypermethrinclinical signshaematology |
| spellingShingle | M. KAMAL SHAH, A. KHAN, F. RIZVI, M. SIDDIQUE1 AND SADEEQ-UR-REHMAN2 EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS Pakistan Veterinary Journal Rabbits cypermethrin clinical signs haematology |
| title | EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS |
| title_full | EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS |
| title_fullStr | EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS |
| title_full_unstemmed | EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS |
| title_short | EFFECT OF CYPERMETHRIN ON CLINICO-HAEMATOLOGICAL PARAMETERS IN RABBITS |
| title_sort | effect of cypermethrin on clinico haematological parameters in rabbits |
| topic | Rabbits cypermethrin clinical signs haematology |
| url | http://pvj.com.pk/pdf-files/27_4/171-175.pdf |
| work_keys_str_mv | AT mkamalshahakhanfrizvimsiddique1andsadeequrrehman2 effectofcypermethrinonclinicohaematologicalparametersinrabbits |