Blimp-1/PRDM1 and Hr3/RORβ specify the blue-sensitive photoreceptor subtype in Drosophila by repressing the hippo pathway

During terminal differentiation of the mammalian retina, transcription factors control binary cell fate decisions that generate functionally distinct subtypes of photoreceptor neurons. For instance, Otx2 and RORβ activate the expression of the transcriptional repressor Blimp-1/PRDM1 that represses b...

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Bibliographic Details
Main Authors: Joseph Bunker, Mhamed Bashir, Sydney Bailey, Pamela Boodram, Alexis Perry, Rory Delaney, Maria Tsachaki, Simon G. Sprecher, Erik Nelson, Gerald B. Call, Jens Rister
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1058961/full

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