9-Phenanthrol, a TRPM4 inhibitor, protects isolated rat hearts from ischemia-reperfusion injury.
Despite efforts to elucidate its pathophysiology, ischemia-reperfusion injury lacks an effective preventative intervention. Because transient receptor potential cation channel subfamily M member 4 (TRPM4) is functionally expressed by many cell types in the cardiovascular system and is involved in th...
Main Authors: | Jing Wang, Ken Takahashi, Hulin Piao, Peng Qu, Keiji Naruse |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3723883?pdf=render |
Similar Items
-
The TRPM4 channel inhibitor 9-phenanthrol alleviates cerebral edema after traumatic brain injury in rats
by: Ping Ma, et al.
Published: (2023-02-01) -
TRPM4 inhibitor 9‐phenanthrol activates endothelial cell intermediate conductance calcium‐activated potassium channels in rat isolated mesenteric artery
by: Garland, C, et al.
Published: (2014) -
Role of the TRPM4 Channel in Cardiovascular Physiology and Pathophysiology
by: Chen Wang, et al.
Published: (2018-06-01) -
Production of TRPM4 knockout cell line using rat cardiomyocyte H9c2
by: Chen Wang, et al.
Published: (2021-01-01) -
Ischemia-Reperfusion Increases TRPM7 Expression in Mouse Retinas
by: Natalia Martínez-Gil, et al.
Published: (2023-11-01)