Shikonin as a WT1 Inhibitor Promotes Promyeloid Leukemia Cell Differentiation

Shikonin as a WT1 Inhibitor Promotes Promyeloid Leukemia Cell Differentiation

This study aims to observe the differentiating effect of shikonin on Wilms’ tumor 1 (WT1)-positive HL-60 cells and investigate the fate of the differentiated leukemia cells. WT1 overexpression unaffected cell viability but promoted resistance to H<sub>2</sub>O<sub>2</sub>-ind...

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Bibliographic Details
Main Authors:	Zhenzhen Guo, Luyao Sun, Haojie Xia, Shibin Tian, Mengyue Liu, Jiejie Hou, Jiahuan Li, Haihong Lin, Gangjun Du
Format:	Article
Language:	English
Published:	MDPI AG 2022-11-01
Series:	Molecules
Subjects:	shikonin leukemia Wilms’ tumor gene 1 (WT1) CD34 cell differentiation
Online Access:	https://www.mdpi.com/1420-3049/27/23/8264

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