Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives
The aim of the study was to examine the applicability of bioactive and antibacterial nanoparticles to an experimental adhesive. The adhesive (60 wt% BisGMA, 15 wt% TEGDMA, 25 wt% HEMA) was mixed with combinations of 5 wt% methacryl-functionalized polyhedral oligomeric silsesquioxane (MA-POSS) and on...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/21/3862 |
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| author | Marietta Kreutz Christian Kreutz Philipp Kanzow Tobias T. Tauböck Phoebe Burrer Christine Noll Oliver Bader Bianca Rohland Annette Wiegand Marta Rizk |
| author_facet | Marietta Kreutz Christian Kreutz Philipp Kanzow Tobias T. Tauböck Phoebe Burrer Christine Noll Oliver Bader Bianca Rohland Annette Wiegand Marta Rizk |
| author_sort | Marietta Kreutz |
| collection | DOAJ |
| description | The aim of the study was to examine the applicability of bioactive and antibacterial nanoparticles to an experimental adhesive. The adhesive (60 wt% BisGMA, 15 wt% TEGDMA, 25 wt% HEMA) was mixed with combinations of 5 wt% methacryl-functionalized polyhedral oligomeric silsesquioxane (MA-POSS) and one kind of bioactive/antibacterial nanoparticles: 1 wt% core-shell silica-silver nanoparticle (SiO<sub>2</sub>@Ag), 1 wt% bioactive glass with bismuth (BAG-Bi) or 1 wt% calcium phosphate (CAP). Pure adhesive served as control. The physicochemical (degree of conversion (DC), linear shrinkage (LS), shear and complex viscosity, water sorption (WS), sol fraction (SF)), biological (antimicrobial effect) and bioactive (mineral precipitation) properties were investigated. DC and LS remained unchanged. The combination of BAG-Bi/MA-POSS resulted in a significantly increased WS and SF compared to control. In addition, the combination of CAP/MA-POSS slightly increased the shear viscosity of the adhesive. The addition of the nanoparticles did not influence the antimicrobial effects compared to the pure adhesive. Improved mineral inducing capacity could be detected in all nanoparticle combinations. The combination of bioactive and/or antibacterial nanoparticles showed improved mineral inducing capacity, but no antibacterial properties. The material properties were not or only slightly affected. |
| first_indexed | 2024-03-09T18:47:09Z |
| format | Article |
| id | doaj.art-95399320202648f9b613781f9982a047 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T18:47:09Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-95399320202648f9b613781f9982a0472023-11-24T06:10:25ZengMDPI AGNanomaterials2079-49912022-11-011221386210.3390/nano12213862Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental AdhesivesMarietta Kreutz0Christian Kreutz1Philipp Kanzow2Tobias T. Tauböck3Phoebe Burrer4Christine Noll5Oliver Bader6Bianca Rohland7Annette Wiegand8Marta Rizk9Department of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, 37075 Göttingen, GermanyDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, 37075 Göttingen, GermanyDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, 37075 Göttingen, GermanyDepartment of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, 8032 Zurich, SwitzerlandDepartment of Conservative and Preventive Dentistry, Center for Dental Medicine, University of Zurich, 8032 Zurich, SwitzerlandInstitute of Medical Microbiology and Virology, University Medical Center Göttingen, 37075 Göttingen, GermanyInstitute of Medical Microbiology and Virology, University Medical Center Göttingen, 37075 Göttingen, GermanyDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, 37075 Göttingen, GermanyDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, 37075 Göttingen, GermanyDepartment of Preventive Dentistry, Periodontology and Cariology, University Medical Center Göttingen, 37075 Göttingen, GermanyThe aim of the study was to examine the applicability of bioactive and antibacterial nanoparticles to an experimental adhesive. The adhesive (60 wt% BisGMA, 15 wt% TEGDMA, 25 wt% HEMA) was mixed with combinations of 5 wt% methacryl-functionalized polyhedral oligomeric silsesquioxane (MA-POSS) and one kind of bioactive/antibacterial nanoparticles: 1 wt% core-shell silica-silver nanoparticle (SiO<sub>2</sub>@Ag), 1 wt% bioactive glass with bismuth (BAG-Bi) or 1 wt% calcium phosphate (CAP). Pure adhesive served as control. The physicochemical (degree of conversion (DC), linear shrinkage (LS), shear and complex viscosity, water sorption (WS), sol fraction (SF)), biological (antimicrobial effect) and bioactive (mineral precipitation) properties were investigated. DC and LS remained unchanged. The combination of BAG-Bi/MA-POSS resulted in a significantly increased WS and SF compared to control. In addition, the combination of CAP/MA-POSS slightly increased the shear viscosity of the adhesive. The addition of the nanoparticles did not influence the antimicrobial effects compared to the pure adhesive. Improved mineral inducing capacity could be detected in all nanoparticle combinations. The combination of bioactive and/or antibacterial nanoparticles showed improved mineral inducing capacity, but no antibacterial properties. The material properties were not or only slightly affected.https://www.mdpi.com/2079-4991/12/21/3862bioactive nanoparticlesantimicrobial nanoparticlesdental adhesivePOSSSiO<sub>2</sub>@Agcalcium phosphate |
| spellingShingle | Marietta Kreutz Christian Kreutz Philipp Kanzow Tobias T. Tauböck Phoebe Burrer Christine Noll Oliver Bader Bianca Rohland Annette Wiegand Marta Rizk Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives Nanomaterials bioactive nanoparticles antimicrobial nanoparticles dental adhesive POSS SiO<sub>2</sub>@Ag calcium phosphate |
| title | Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives |
| title_full | Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives |
| title_fullStr | Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives |
| title_full_unstemmed | Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives |
| title_short | Effect of Bioactive and Antimicrobial Nanoparticles on Properties and Applicability of Dental Adhesives |
| title_sort | effect of bioactive and antimicrobial nanoparticles on properties and applicability of dental adhesives |
| topic | bioactive nanoparticles antimicrobial nanoparticles dental adhesive POSS SiO<sub>2</sub>@Ag calcium phosphate |
| url | https://www.mdpi.com/2079-4991/12/21/3862 |
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