Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information
Background: Pharmacogenomics is the study of how genes affect a person’s response to drugs. This descriptive study assessed whether popular drug information resources provide clinically useful pharmacogenomic (PGx) information. Methods: Four resources (package inserts, Lexicomp, Micromedex 2.0, and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
University Library System, University of Pittsburgh
2016-01-01
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| Series: | Journal of the Medical Library Association |
| Subjects: | |
| Online Access: | http://jmla.pitt.edu/ojs/jmla/article/view/367 |
| Summary: | Background: Pharmacogenomics is the study of how genes affect a person’s response to drugs. This descriptive study assessed whether popular drug information resources provide clinically useful pharmacogenomic (PGx) information.
Methods: Four resources (package inserts, Lexicomp, Micromedex 2.0, and Epocrates) were evaluated for information about twenty-seven drugs.
Results: There was wide variability of PGx information. Whereas Lexicomp included relevant PGx biomarker information for all 27 drugs, Epocrates did in less than 50% of the drugs. None of the resources had monographs that fully incorporated Clinical Pharmacogenomics Implementation Consortium (CPIC) recommendations in more than 30% of the drugs.
Conclusion: Lexicomp appears to be most useful PGx drug information resource, but none of the resources are sufficient. |
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| ISSN: | 1536-5050 1558-9439 |