Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information
Background: Pharmacogenomics is the study of how genes affect a person’s response to drugs. This descriptive study assessed whether popular drug information resources provide clinically useful pharmacogenomic (PGx) information. Methods: Four resources (package inserts, Lexicomp, Micromedex 2.0, and...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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University Library System, University of Pittsburgh
2016-01-01
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| Series: | Journal of the Medical Library Association |
| Subjects: | |
| Online Access: | http://jmla.pitt.edu/ojs/jmla/article/view/367 |
| _version_ | 1811303209230139392 |
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| author | Jennifer S. Chang Duyen-Anh Pham Maithao T. Dang Yiting Lu Sheri VanOsdol Jaekyu Shin |
| author_facet | Jennifer S. Chang Duyen-Anh Pham Maithao T. Dang Yiting Lu Sheri VanOsdol Jaekyu Shin |
| author_sort | Jennifer S. Chang |
| collection | DOAJ |
| description | Background: Pharmacogenomics is the study of how genes affect a person’s response to drugs. This descriptive study assessed whether popular drug information resources provide clinically useful pharmacogenomic (PGx) information.
Methods: Four resources (package inserts, Lexicomp, Micromedex 2.0, and Epocrates) were evaluated for information about twenty-seven drugs.
Results: There was wide variability of PGx information. Whereas Lexicomp included relevant PGx biomarker information for all 27 drugs, Epocrates did in less than 50% of the drugs. None of the resources had monographs that fully incorporated Clinical Pharmacogenomics Implementation Consortium (CPIC) recommendations in more than 30% of the drugs.
Conclusion: Lexicomp appears to be most useful PGx drug information resource, but none of the resources are sufficient. |
| first_indexed | 2024-04-13T07:42:40Z |
| format | Article |
| id | doaj.art-953de7e2aabe4fff8c4b1ef751018a2d |
| institution | Directory Open Access Journal |
| issn | 1536-5050 1558-9439 |
| language | English |
| last_indexed | 2024-04-13T07:42:40Z |
| publishDate | 2016-01-01 |
| publisher | University Library System, University of Pittsburgh |
| record_format | Article |
| series | Journal of the Medical Library Association |
| spelling | doaj.art-953de7e2aabe4fff8c4b1ef751018a2d2022-12-22T02:55:49ZengUniversity Library System, University of PittsburghJournal of the Medical Library Association1536-50501558-94392016-01-011041210Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic informationJennifer S. Chang0Duyen-Anh Pham1Maithao T. Dang2Yiting Lu3Sheri VanOsdol4Jaekyu Shin5Pharmacy Student (at the time of the study), Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, 533 Parnassus Avenue, U-585, Box 0622, San Francisco, CA 94143-0622Pharmacy Student (at the time of the study), Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, 533 Parnassus Avenue, U-585, Box 0622, San Francisco, CA 94143-0622Pharmacy Student (at the time of the study), Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, 533 Parnassus Avenue, U-585, Box 0622, San Francisco, CA 94143-0622Pharmacy Student (at the time of the study), Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, 533 Parnassus Avenue, U-585, Box 0622, San Francisco, CA 94143-0622Assistant Professor of Clinical Pharmacy (at the time of the study), Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, 533 Parnassus Avenue, U-585, Box 0622, San Francisco, CA 94143-0622Associate Professor of Clinical Pharmacy, Department of Clinical Pharmacy, School of Pharmacy, University of California San Francisco, 533 Parnassus Avenue, U-585, Box 0622, San Francisco, CA 94143-0622Background: Pharmacogenomics is the study of how genes affect a person’s response to drugs. This descriptive study assessed whether popular drug information resources provide clinically useful pharmacogenomic (PGx) information. Methods: Four resources (package inserts, Lexicomp, Micromedex 2.0, and Epocrates) were evaluated for information about twenty-seven drugs. Results: There was wide variability of PGx information. Whereas Lexicomp included relevant PGx biomarker information for all 27 drugs, Epocrates did in less than 50% of the drugs. None of the resources had monographs that fully incorporated Clinical Pharmacogenomics Implementation Consortium (CPIC) recommendations in more than 30% of the drugs. Conclusion: Lexicomp appears to be most useful PGx drug information resource, but none of the resources are sufficient.http://jmla.pitt.edu/ojs/jmla/article/view/367Pharmacogenomics, Biomarkers, Drug Information Services, Genetic Testing |
| spellingShingle | Jennifer S. Chang Duyen-Anh Pham Maithao T. Dang Yiting Lu Sheri VanOsdol Jaekyu Shin Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information Journal of the Medical Library Association Pharmacogenomics, Biomarkers, Drug Information Services, Genetic Testing |
| title | Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information |
| title_full | Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information |
| title_fullStr | Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information |
| title_full_unstemmed | Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information |
| title_short | Evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information |
| title_sort | evaluation of popular drug information resources on clinically useful and actionable pharmacogenomic information |
| topic | Pharmacogenomics, Biomarkers, Drug Information Services, Genetic Testing |
| url | http://jmla.pitt.edu/ojs/jmla/article/view/367 |
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