THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID

Clinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied. The obtained results testify to the fact that the expressed local h...

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Bibliographic Details
Main Authors: V I Shishkin, G. V. Kudriavtzeva, A B Ryabkov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2001-10-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/607
Description
Summary:Clinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied. The obtained results testify to the fact that the expressed local hypoxia of cartilage tissue favoring the development, conserving and chronization of inflammatory process in synovial environment of knee joint in О A is successfully arrested by the above drug. Simultaneously bio-energetic parameters of synovial fluid were normalized: the level of oxygen absorption by synovial cells, the activity of a number of enzymes of hydrogen-phosphor (energetic) metabolism as well as of glucuronidaze and gialuronidaze,
ISSN:1995-4484
1995-4492