THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID

Clinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied. The obtained results testify to the fact that the expressed local h...

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Main Authors: V I Shishkin, G. V. Kudriavtzeva, A B Ryabkov
Format: Article
Language:Russian
Published: IMA PRESS LLC 2001-10-01
Series:Научно-практическая ревматология
Subjects:
Online Access:https://rsp.mediar-press.net/rsp/article/view/607
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author V I Shishkin
G. V. Kudriavtzeva
A B Ryabkov
author_facet V I Shishkin
G. V. Kudriavtzeva
A B Ryabkov
author_sort V I Shishkin
collection DOAJ
description Clinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied. The obtained results testify to the fact that the expressed local hypoxia of cartilage tissue favoring the development, conserving and chronization of inflammatory process in synovial environment of knee joint in О A is successfully arrested by the above drug. Simultaneously bio-energetic parameters of synovial fluid were normalized: the level of oxygen absorption by synovial cells, the activity of a number of enzymes of hydrogen-phosphor (energetic) metabolism as well as of glucuronidaze and gialuronidaze,
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spelling doaj.art-953e241ab9d148db9731f60c6c56d5552023-03-22T13:45:37ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922001-10-01395343810.14412/1995-4484-2001-469547THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUIDV I ShishkinG. V. KudriavtzevaA B RyabkovClinical and laboratory study was carried out including 30 pts with definite diagnosis of osteoarthritis (OA ) of knee joint. The effect of chondroitin sulfate (Structum) on basic bio-energetic indices of synovial fluid was studied. The obtained results testify to the fact that the expressed local hypoxia of cartilage tissue favoring the development, conserving and chronization of inflammatory process in synovial environment of knee joint in О A is successfully arrested by the above drug. Simultaneously bio-energetic parameters of synovial fluid were normalized: the level of oxygen absorption by synovial cells, the activity of a number of enzymes of hydrogen-phosphor (energetic) metabolism as well as of glucuronidaze and gialuronidaze,https://rsp.mediar-press.net/rsp/article/view/607osteoarthritisprostaglandinsenzymes of carbohvdrate-phosphorus metabolismchondroitin sulfateacid liydrolazesoxvven absorption rateoxidation phosphorolvsis
spellingShingle V I Shishkin
G. V. Kudriavtzeva
A B Ryabkov
THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
Научно-практическая ревматология
osteoarthritis
prostaglandins
enzymes of carbohvdrate-phosphorus metabolism
chondroitin sulfate
acid liydrolazes
oxvven absorption rate
oxidation phosphorolvsis
title THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
title_full THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
title_fullStr THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
title_full_unstemmed THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
title_short THE EFFICASY OF STRUCTUM (CHONDROITIN SULFATE) ON BIOENERGETIC CHARACTERISTICS OF OA SYNOVIAL FLUID
title_sort efficasy of structum chondroitin sulfate on bioenergetic characteristics of oa synovial fluid
topic osteoarthritis
prostaglandins
enzymes of carbohvdrate-phosphorus metabolism
chondroitin sulfate
acid liydrolazes
oxvven absorption rate
oxidation phosphorolvsis
url https://rsp.mediar-press.net/rsp/article/view/607
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