Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women
Background: With limited health data on Arab Americans (AAs), we sought to describe the health-seeking behaviors, prevalence of abnormal cervical cytology and high-risk human papillomavirus (HPV) serotypes, and the relationship with socioeconomic factors among a subset of AA women. Methods: Retrospe...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Mary Ann Liebert
2021-07-01
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| Series: | Women's Health Reports |
| Subjects: | |
| Online Access: | https://www.liebertpub.com/doi/full/10.1089/WHR.2020.0129 |
| _version_ | 1797345792144441344 |
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| author | Anita Shallal Evi Abada Ziad Fehmi Saivaishnavi Kamatham Joseph Trak Omar Fehmi Andrew Toma Sarah Farooqi Hyejeong Jang Seongho Kim Sudeshna Bandyopadhyay Marcus Zervos Rouba Ali-Fehmi |
| author_facet | Anita Shallal Evi Abada Ziad Fehmi Saivaishnavi Kamatham Joseph Trak Omar Fehmi Andrew Toma Sarah Farooqi Hyejeong Jang Seongho Kim Sudeshna Bandyopadhyay Marcus Zervos Rouba Ali-Fehmi |
| author_sort | Anita Shallal |
| collection | DOAJ |
| description | Background: With limited health data on Arab Americans (AAs), we sought to describe the health-seeking behaviors, prevalence of abnormal cervical cytology and high-risk human papillomavirus (HPV) serotypes, and the relationship with socioeconomic factors among a subset of AA women.
Methods: Retrospective observational cohort study of women undergoing routine cancer screening at the Arab-American Center for Economic and Social Services clinic. Data collected included demographics, tobacco use, gross monthly income, prior Papanicolaou (Pap) smear history, and results of cervical cytology and high-risk HPV testing.
Results: Of 430 women, 74 (17%) reported that they had never had a Pap smear. Three hundred eighty-eight (90%) women had cervical cytology interpreted as ?negative for intraepithelial lesion,? the remaining 42 (10%) women had abnormal results. Thirteen (3%) women reported prior abnormal Pap smear, which was significantly associated with additional abnormal Pap smear on multivariable analyses (odds ratio 65.46; 95% confidence interval [CI] 17.01?338.62; p?<?0.001). One hundred twenty-five (29%) women were tested for high-risk HPV serotypes; 106 (91%) had negative results, 4 (3%) were positive for HPV-16, 7 (6%) were positive for other high-risk serotypes, and 8 results were not recorded. A negative HPV screen was significantly associated with a negative Pap smear (Fisher's exact test p?=?0.006). There was no significant association between abnormal cervical cytology and evaluated socioeconomic factors.
Conclusions: Additional population based-studies to determine cervical dysplasia/cancer and HPV prevalence in women of Middle Eastern descent are needed. |
| first_indexed | 2024-03-08T11:23:52Z |
| format | Article |
| id | doaj.art-9540d31ff1bd4868bf718f909fbed207 |
| institution | Directory Open Access Journal |
| issn | 2688-4844 |
| language | English |
| last_indexed | 2024-03-08T11:23:52Z |
| publishDate | 2021-07-01 |
| publisher | Mary Ann Liebert |
| record_format | Article |
| series | Women's Health Reports |
| spelling | doaj.art-9540d31ff1bd4868bf718f909fbed2072024-01-26T05:40:56ZengMary Ann LiebertWomen's Health Reports2688-48442021-07-012127327810.1089/WHR.2020.0129Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American WomenAnita ShallalEvi AbadaZiad FehmiSaivaishnavi KamathamJoseph TrakOmar FehmiAndrew TomaSarah FarooqiHyejeong JangSeongho KimSudeshna BandyopadhyayMarcus ZervosRouba Ali-FehmiBackground: With limited health data on Arab Americans (AAs), we sought to describe the health-seeking behaviors, prevalence of abnormal cervical cytology and high-risk human papillomavirus (HPV) serotypes, and the relationship with socioeconomic factors among a subset of AA women. Methods: Retrospective observational cohort study of women undergoing routine cancer screening at the Arab-American Center for Economic and Social Services clinic. Data collected included demographics, tobacco use, gross monthly income, prior Papanicolaou (Pap) smear history, and results of cervical cytology and high-risk HPV testing. Results: Of 430 women, 74 (17%) reported that they had never had a Pap smear. Three hundred eighty-eight (90%) women had cervical cytology interpreted as ?negative for intraepithelial lesion,? the remaining 42 (10%) women had abnormal results. Thirteen (3%) women reported prior abnormal Pap smear, which was significantly associated with additional abnormal Pap smear on multivariable analyses (odds ratio 65.46; 95% confidence interval [CI] 17.01?338.62; p?<?0.001). One hundred twenty-five (29%) women were tested for high-risk HPV serotypes; 106 (91%) had negative results, 4 (3%) were positive for HPV-16, 7 (6%) were positive for other high-risk serotypes, and 8 results were not recorded. A negative HPV screen was significantly associated with a negative Pap smear (Fisher's exact test p?=?0.006). There was no significant association between abnormal cervical cytology and evaluated socioeconomic factors. Conclusions: Additional population based-studies to determine cervical dysplasia/cancer and HPV prevalence in women of Middle Eastern descent are needed.https://www.liebertpub.com/doi/full/10.1089/WHR.2020.0129HPVArab American womencervical cancer screeningPap smearcervical dysplasia |
| spellingShingle | Anita Shallal Evi Abada Ziad Fehmi Saivaishnavi Kamatham Joseph Trak Omar Fehmi Andrew Toma Sarah Farooqi Hyejeong Jang Seongho Kim Sudeshna Bandyopadhyay Marcus Zervos Rouba Ali-Fehmi Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women Women's Health Reports HPV Arab American women cervical cancer screening Pap smear cervical dysplasia |
| title | Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women |
| title_full | Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women |
| title_fullStr | Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women |
| title_full_unstemmed | Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women |
| title_short | Human Papillomavirus Infection and Cervical Dysplasia in a Subset of Arab American Women |
| title_sort | human papillomavirus infection and cervical dysplasia in a subset of arab american women |
| topic | HPV Arab American women cervical cancer screening Pap smear cervical dysplasia |
| url | https://www.liebertpub.com/doi/full/10.1089/WHR.2020.0129 |
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