Vitamin D Levels In Children with Bronchial Asthma
Introduction: Bronchial Asthma is a common chronic inflammatory disorder of the airways in childhood. Vitamin-D, required for bone mineralization, is also a potent immune system regulator having a potential role in various allergic diseases. This study was undertaken to determine the difference...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2014-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/5055/10387_CE(Ra)_F(Sh)_PF1(AJAK)_PFA(Sh)_PF2(PAG).pdf |
| Summary: | Introduction: Bronchial Asthma is a common chronic
inflammatory disorder of the airways in childhood. Vitamin-D,
required for bone mineralization, is also a potent immune system
regulator having a potential role in various allergic diseases.
This study was undertaken to determine the difference in serum
levels of Vitamin-D in asthmatic children and to determine the
association between vitamin-D and asthma in children.
Materials and Methods: This cross-sectional study included
88 (44 asthmatic children and 44 healthy controls) children
aged between 5 and 13 y. Serum 25-hydroxy vitamin-D levels
were determined and compared between the two groups. The
association between vitamin-D levels and lung function was
studied in the asthmatic children.
Results: Serum vitamin-D level was significantly lower in
asthmatic children than in control group and in the asthmatic
group, vitamin-D levels had a significant positive correlation
with FEV1% and FEV1/FVC%.
Conclusion: Vitamin-D deficiency is highly prevalent in
asthmatic children and is associated with airway limitation. |
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| ISSN: | 2249-782X 0973-709X |