Prevalence of preterm labor in Iran: A systematic review and meta-analysis

Background: Preterm labor, which defines as live-birth delivery before 37 weeks of gestation is a main determinant of neonatal morbidity and mortality around the world. Objective: The aim of this study was to determine the prevalence of preterm labor in Iran by a meta-analysis study, to be as a...

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Main Authors: Katayon Vakilian, Mehdi Ranjbaran, Mahboobeh Khorsandi, Naser Sharafkhani, Mahmoud Khodadost
Format: Article
Language:English
Published: Shahid Sadoughi University of Medical Science, Yazd, Iran 2015-12-01
Series:Iranian Journal of Reproductive Medicine
Online Access:http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1768/920
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author Katayon Vakilian
Mehdi Ranjbaran
Mahboobeh Khorsandi
Naser Sharafkhani
Mahmoud Khodadost
author_facet Katayon Vakilian
Mehdi Ranjbaran
Mahboobeh Khorsandi
Naser Sharafkhani
Mahmoud Khodadost
author_sort Katayon Vakilian
collection DOAJ
description Background: Preterm labor, which defines as live-birth delivery before 37 weeks of gestation is a main determinant of neonatal morbidity and mortality around the world. Objective: The aim of this study was to determine the prevalence of preterm labor in Iran by a meta-analysis study, to be as a final measure for policy makers in this field. Materials and Methods: In this meta-analysis, the databases of Thomson database (Web of Knowledge), PubMed/Medline, Science Direct, Scopus, Google Scholar, Iranmedex, Scientific Information Database (SID), Magiran, and Medlib were searched for articles in English and Persian language published between 1995 and 2014. Among the studies with regard to the inclusion and exclusion criteria, 14 studies (out of 1370 publications) were selected. Data were analyzed by using Stata software version 11. The heterogeneity of reported prevalence among studies was evaluated by the Chi-square based Q test and I2 statistics. Results: The results of Chi-square based on Q test and I2 statistics revealed severe heterogeneity (Q=2505.12, p-value < 0.001 and I2= 99.5%) and consequently, the random effect model was used for the meta-analysis. Based on the random effect model, the overall estimated prevalence of preterm in Iran was 9.2% (95% CI: 7.6 – 10.7). Conclusion: Present study summarized the results of previous studies and provided a comprehensive view about the preterm delivery in Iran. In order to achieve a more desirable level and its reduction in the coming years, identifying affecting factor and interventional and preventive actions seem necessary.
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spelling doaj.art-9541faf61b8d460ebadca75de412d8542022-12-22T01:37:04ZengShahid Sadoughi University of Medical Science, Yazd, IranIranian Journal of Reproductive Medicine1680-64332008-21772015-12-011312743748Prevalence of preterm labor in Iran: A systematic review and meta-analysisKatayon Vakilian0Mehdi Ranjbaran1Mahboobeh Khorsandi2Naser Sharafkhani3Mahmoud Khodadost4Faculty of Nursing and Midwifery, Arak University of Medical Sciences, Arak, Iran.Department of Epidemiology, Faculty of Health, Arak University of Medical Sciences, Arak, Iran.Department of Health Education and Health Promotion, Faculty of Health, Arak University of Medical Sciences, Arak, Iran.Department of Health Education and Health Promotion, Faculty of Health, Arak University of Medical Sciences, Arak, Iran.Gastroenterology and Liver Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.Background: Preterm labor, which defines as live-birth delivery before 37 weeks of gestation is a main determinant of neonatal morbidity and mortality around the world. Objective: The aim of this study was to determine the prevalence of preterm labor in Iran by a meta-analysis study, to be as a final measure for policy makers in this field. Materials and Methods: In this meta-analysis, the databases of Thomson database (Web of Knowledge), PubMed/Medline, Science Direct, Scopus, Google Scholar, Iranmedex, Scientific Information Database (SID), Magiran, and Medlib were searched for articles in English and Persian language published between 1995 and 2014. Among the studies with regard to the inclusion and exclusion criteria, 14 studies (out of 1370 publications) were selected. Data were analyzed by using Stata software version 11. The heterogeneity of reported prevalence among studies was evaluated by the Chi-square based Q test and I2 statistics. Results: The results of Chi-square based on Q test and I2 statistics revealed severe heterogeneity (Q=2505.12, p-value < 0.001 and I2= 99.5%) and consequently, the random effect model was used for the meta-analysis. Based on the random effect model, the overall estimated prevalence of preterm in Iran was 9.2% (95% CI: 7.6 – 10.7). Conclusion: Present study summarized the results of previous studies and provided a comprehensive view about the preterm delivery in Iran. In order to achieve a more desirable level and its reduction in the coming years, identifying affecting factor and interventional and preventive actions seem necessary.http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1768/920
spellingShingle Katayon Vakilian
Mehdi Ranjbaran
Mahboobeh Khorsandi
Naser Sharafkhani
Mahmoud Khodadost
Prevalence of preterm labor in Iran: A systematic review and meta-analysis
Iranian Journal of Reproductive Medicine
title Prevalence of preterm labor in Iran: A systematic review and meta-analysis
title_full Prevalence of preterm labor in Iran: A systematic review and meta-analysis
title_fullStr Prevalence of preterm labor in Iran: A systematic review and meta-analysis
title_full_unstemmed Prevalence of preterm labor in Iran: A systematic review and meta-analysis
title_short Prevalence of preterm labor in Iran: A systematic review and meta-analysis
title_sort prevalence of preterm labor in iran a systematic review and meta analysis
url http://www.ssu.ac.ir/ijrm/index.php/ijrm/article/view/1768/920
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