Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles
Cycloaddition reactions of alkynes are elegant, atom-efficient transformations for the synthesis of carbo- and heterocycles, mostly aromatic, involving the construction of challenging skeletons of complex molecules. Therefore significant efforts have recently been devoted to the development of novel...
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MDPI AG
2014-09-01
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Series: | Molecules |
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Online Access: | http://www.mdpi.com/1420-3049/19/9/13788 |
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author | Tauqir A. Nizami Ruimao Hua |
author_facet | Tauqir A. Nizami Ruimao Hua |
author_sort | Tauqir A. Nizami |
collection | DOAJ |
description | Cycloaddition reactions of alkynes are elegant, atom-efficient transformations for the synthesis of carbo- and heterocycles, mostly aromatic, involving the construction of challenging skeletons of complex molecules. Therefore significant efforts have recently been devoted to the development of novel methodologies, efficient strategies and different catalytic systems to broaden the scope of these reactions. We summarize in this review the recent advances in the cycloaddition reactions of 1,3-butadiynes to provide facile and reliable approaches to various functionalized carbo- and heterocycles. |
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format | Article |
id | doaj.art-9544c1de3d67400a8b6261c1a88a0e80 |
institution | Directory Open Access Journal |
issn | 1420-3049 |
language | English |
last_indexed | 2024-04-14T01:51:42Z |
publishDate | 2014-09-01 |
publisher | MDPI AG |
record_format | Article |
series | Molecules |
spelling | doaj.art-9544c1de3d67400a8b6261c1a88a0e802022-12-22T02:19:19ZengMDPI AGMolecules1420-30492014-09-01199137881380210.3390/molecules190913788molecules190913788Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and HeterocyclesTauqir A. Nizami0Ruimao Hua1Department of Chemistry, Tsinghua University, Beijing 100084, ChinaDepartment of Chemistry, Tsinghua University, Beijing 100084, ChinaCycloaddition reactions of alkynes are elegant, atom-efficient transformations for the synthesis of carbo- and heterocycles, mostly aromatic, involving the construction of challenging skeletons of complex molecules. Therefore significant efforts have recently been devoted to the development of novel methodologies, efficient strategies and different catalytic systems to broaden the scope of these reactions. We summarize in this review the recent advances in the cycloaddition reactions of 1,3-butadiynes to provide facile and reliable approaches to various functionalized carbo- and heterocycles.http://www.mdpi.com/1420-3049/19/9/137881,3-butadiynescycloadditioncabocyclesheterocycles |
spellingShingle | Tauqir A. Nizami Ruimao Hua Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles Molecules 1,3-butadiynes cycloaddition cabocycles heterocycles |
title | Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles |
title_full | Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles |
title_fullStr | Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles |
title_full_unstemmed | Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles |
title_short | Cycloaddition of 1,3-Butadiynes: Efficient Synthesis of Carbo- and Heterocycles |
title_sort | cycloaddition of 1 3 butadiynes efficient synthesis of carbo and heterocycles |
topic | 1,3-butadiynes cycloaddition cabocycles heterocycles |
url | http://www.mdpi.com/1420-3049/19/9/13788 |
work_keys_str_mv | AT tauqiranizami cycloadditionof13butadiynesefficientsynthesisofcarboandheterocycles AT ruimaohua cycloadditionof13butadiynesefficientsynthesisofcarboandheterocycles |