A Redesigned Method for CNP-Synchronized In Vitro Maturation Inhibits Oxidative Stress and Apoptosis in Cumulus-Oocyte Complexes and Improves the Developmental Potential of Porcine Oocytes

A Redesigned Method for CNP-Synchronized In Vitro Maturation Inhibits Oxidative Stress and Apoptosis in Cumulus-Oocyte Complexes and Improves the Developmental Potential of Porcine Oocytes

In vitro embryo production depends on high-quality oocytes. Compared with in vivo matured oocytes, in vitro oocytes undergo precocious meiotic resumption, thus compromising oocyte quality. C-type natriuretic peptide (CNP) is a follicular factor maintaining meiotic arrest. Thus, CNP-pretreatment has...

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Bibliographic Details
Main Authors: Jinlun Lu, Min Guo, Xiaodong Wang, Rui Wang, Guangyin Xi, Lei An, Jianhui Tian, Meiqiang Chu
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Genes
Subjects:
C-type natriuretic peptide
meiotic arrest
in vitro maturation
developmental potential
porcine oocytes
Online Access:https://www.mdpi.com/2073-4425/14/10/1885

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