Investigation of Cytotoxic Effects of Recombinant Human Interferon Lambda-1 and Its Pegylated Form on Human Conjunctival Epithelial Cells

Investigation of Cytotoxic Effects of Recombinant Human Interferon Lambda-1 and Its Pegylated Form on Human Conjunctival Epithelial Cells

Currently, there are no efficacious, all-purpose antiviral medicines for the treatment of ocular surface infections caused by viruses. At the same time, type III interferons demonstrate high potency for histological barriers, such as the conjunctiva. Modification of protein molecules in native produ...

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Bibliographic Details
Main Authors: N. A. Kikhtenko, N. A. Bondarenko, N. P. Bgatova, L. A. Oleynik, O. V. Poveshchenko, A. Zh. Fursova, P. G. Madonov
Format: Article
Language:Russian
Published: Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2021-12-01
Series:Безопасность и риск фармакотерапии
Subjects:
interferon
interferon lambda
pegylation
human conjunctiva
cytotoxicity
normal human conjunctiva cell line
Online Access:https://www.risksafety.ru/jour/article/view/240

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