Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia–Reperfusion

Neuroprotective Effects of the Lithium Salt of a Novel JNK Inhibitor in an Animal Model of Cerebral Ischemia–Reperfusion

The c-Jun <i>N</i>-terminal kinases (JNKs) regulate many physiological processes, including inflammatory responses, morphogenesis, cell proliferation, differentiation, survival, and cell death. Therefore, JNKs represent attractive targets for therapeutic intervention. In an effort to dev...

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Bibliographic Details
Main Authors: Igor A. Schepetkin, Galina A. Chernysheva, Oleg I. Aliev, Liliya N. Kirpotina, Vera I. Smol’yakova, Anton N. Osipenko, Mark B. Plotnikov, Anastasia R. Kovrizhina, Andrei I. Khlebnikov, Evgenii V. Plotnikov, Mark T. Quinn
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biomedicines
Subjects:
c-Jun <i>N</i>-terminal kinase
11<i>H</i>-indeno[1,2-<i>b</i>]quinoxalin-11-one
oxime
interleukin-6
nuclear factor-κB
lithium salt
Online Access:https://www.mdpi.com/2227-9059/10/9/2119

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