Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs

BackgroundThe common methods of radiographic diagnosis of developmental dysplasia of the hip (DDH) include measuring hip parameters and quantifying the degree of hip dislocation. However, clinical thought-based analysis of hip parameters may be a more effective way to achieve expert-like diagnoses o...

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Main Authors: Jia Sha, Luyu Huang, Yaopeng Chen, Zongzhi Fan, Jincong Lin, Qinghai Yang, Yi Li, Yabo Yan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2023.1080194/full
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author Jia Sha
Luyu Huang
Yaopeng Chen
Yaopeng Chen
Zongzhi Fan
Jincong Lin
Qinghai Yang
Yi Li
Yabo Yan
author_facet Jia Sha
Luyu Huang
Yaopeng Chen
Yaopeng Chen
Zongzhi Fan
Jincong Lin
Qinghai Yang
Yi Li
Yabo Yan
author_sort Jia Sha
collection DOAJ
description BackgroundThe common methods of radiographic diagnosis of developmental dysplasia of the hip (DDH) include measuring hip parameters and quantifying the degree of hip dislocation. However, clinical thought-based analysis of hip parameters may be a more effective way to achieve expert-like diagnoses of DDH. This study aims to develop a diagnostic strategy-based software for pediatric DDH and validate its clinical feasibility.MethodsIn total, 543 anteroposterior pelvic radiographs were retrospectively collected from January 2017 to December 2021. Two independent clinicians measured four diagnostic indices to compare the diagnoses made by the software and conventional manual method. The diagnostic accuracy was evaluated using the receiver operator characteristic (ROC) curves and confusion matrix, and the consistency of parametric measurements was assessed using Bland-Altman plots.ResultsIn 543 cases (1,086 hips), the area under the curve, accuracy, sensitivity, and specificity of the software for diagnosing DDH were 0.988–0.994, 99.08%–99.72%, 98.07%–100.00%, and 99.59%, respectively. Compared with the expert panel, the Bland-Altman 95% limits of agreement for the acetabular index, as determined by the software, were −2.09°–2.91° (junior orthopedist) and −1.98°–2.72° (intermediate orthopedist). As for the lateral center-edge angle, the 95% limits were −3.68°–5.28° (junior orthopedist) and −2.94°–4.59° (intermediate orthopedist).ConclusionsThe software can provide expert-like analysis of pelvic radiographs and obtain the radiographic diagnosis of pediatric DDH with great consistency and efficiency. Its initial success lays the groundwork for developing a full-intelligent comprehensive diagnostic system of DDH.
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spelling doaj.art-95504f5fb760448fb1797361021086a32023-03-30T06:52:12ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-03-011110.3389/fped.2023.10801941080194Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographsJia Sha0Luyu Huang1Yaopeng Chen2Yaopeng Chen3Zongzhi Fan4Jincong Lin5Qinghai Yang6Yi Li7Yabo Yan8Department of Orthopedics, Xijing Hospital, Air Force Military Medical University, Xi’an, ChinaDepartment of Orthopedics, Xijing Hospital, Air Force Military Medical University, Xi’an, ChinaSchool of Telecommunications Engineering, Xidian University, Xi’an, ChinaGuangzhou Institute, Xidian University, Xi’an, ChinaDepartment of Orthopedics, Xijing Hospital, Air Force Military Medical University, Xi’an, ChinaDepartment of Orthopedics, Xijing Hospital, Air Force Military Medical University, Xi’an, ChinaSchool of Telecommunications Engineering, Xidian University, Xi’an, ChinaSchool of Telecommunications Engineering, Xidian University, Xi’an, ChinaDepartment of Orthopedics, Xijing Hospital, Air Force Military Medical University, Xi’an, ChinaBackgroundThe common methods of radiographic diagnosis of developmental dysplasia of the hip (DDH) include measuring hip parameters and quantifying the degree of hip dislocation. However, clinical thought-based analysis of hip parameters may be a more effective way to achieve expert-like diagnoses of DDH. This study aims to develop a diagnostic strategy-based software for pediatric DDH and validate its clinical feasibility.MethodsIn total, 543 anteroposterior pelvic radiographs were retrospectively collected from January 2017 to December 2021. Two independent clinicians measured four diagnostic indices to compare the diagnoses made by the software and conventional manual method. The diagnostic accuracy was evaluated using the receiver operator characteristic (ROC) curves and confusion matrix, and the consistency of parametric measurements was assessed using Bland-Altman plots.ResultsIn 543 cases (1,086 hips), the area under the curve, accuracy, sensitivity, and specificity of the software for diagnosing DDH were 0.988–0.994, 99.08%–99.72%, 98.07%–100.00%, and 99.59%, respectively. Compared with the expert panel, the Bland-Altman 95% limits of agreement for the acetabular index, as determined by the software, were −2.09°–2.91° (junior orthopedist) and −1.98°–2.72° (intermediate orthopedist). As for the lateral center-edge angle, the 95% limits were −3.68°–5.28° (junior orthopedist) and −2.94°–4.59° (intermediate orthopedist).ConclusionsThe software can provide expert-like analysis of pelvic radiographs and obtain the radiographic diagnosis of pediatric DDH with great consistency and efficiency. Its initial success lays the groundwork for developing a full-intelligent comprehensive diagnostic system of DDH.https://www.frontiersin.org/articles/10.3389/fped.2023.1080194/fulldevelopmental dysplasia of the hipchildrenpelvic radiographdiagnosissoftware
spellingShingle Jia Sha
Luyu Huang
Yaopeng Chen
Yaopeng Chen
Zongzhi Fan
Jincong Lin
Qinghai Yang
Yi Li
Yabo Yan
Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
Frontiers in Pediatrics
developmental dysplasia of the hip
children
pelvic radiograph
diagnosis
software
title Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
title_full Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
title_fullStr Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
title_full_unstemmed Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
title_short Clinical thought-based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
title_sort clinical thought based software for diagnosing developmental dysplasia of the hip on pediatric pelvic radiographs
topic developmental dysplasia of the hip
children
pelvic radiograph
diagnosis
software
url https://www.frontiersin.org/articles/10.3389/fped.2023.1080194/full
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