Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole

Purpose: To report a case where the induction of macular edema with topical latanoprost coupled with in-office gas injection effectively sealed a persistent, chronic, macular hole. Observations: A 70-year-old, pseudophakic, patient presented with a stage three, chronic, macular hole (MH) and vision...

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Main Authors: H Logan Brooks, Jr., Cuneyt Ozkardes
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:American Journal of Ophthalmology Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2451993622003498
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author H Logan Brooks, Jr.
Cuneyt Ozkardes
author_facet H Logan Brooks, Jr.
Cuneyt Ozkardes
author_sort H Logan Brooks, Jr.
collection DOAJ
description Purpose: To report a case where the induction of macular edema with topical latanoprost coupled with in-office gas injection effectively sealed a persistent, chronic, macular hole. Observations: A 70-year-old, pseudophakic, patient presented with a stage three, chronic, macular hole (MH) and vision reduced to 20/200. The symptoms had been present for 18 months. Patient had surgery with pars plana vitrectomy (PPV), complete internal limiting membrane (ILM) peel to the arcades, 30% SF6 gas, and excellent face down positioning for five days. Two weeks after surgery the macular hole failed to close, and the edges of the hole were blunted with very little retinal edema and vision reduced to 20/400. The patient did not want to go back to the operating room. After informed consent, the patient was started on topical latanoprost 0.005% on the operative eye twice a day for six weeks. After latanoprost induction of cystoid macular edema (CME), the patient had 0.7 cc of pure C3F8 injected into the vitreous cavity in the office and was instructed to be face down for five days. Two weeks later the macular hole was closed with vision of 20/80. Last corrected vision eight months later was 20/50. Conclusions and Importance: The findings in this case suggest that induction of CME facilitated the closure of a chronic, persistent, macular hole with a simple gas injection in the office and face down positioning for five days.
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spelling doaj.art-9552e6da04a547379b35f613c6218b122022-12-22T04:03:16ZengElsevierAmerican Journal of Ophthalmology Case Reports2451-99362022-09-0127101603Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular holeH Logan Brooks, Jr.0Cuneyt Ozkardes1Southern Vitreoretinal Associates, 2439 Care Rd, Tallahassee, FL, 32308, USA; Corresponding author. 2439 Care Rd, Tallahassee, FL, 32308, USA.Florida State University College of Medicine, 1115 West Call St, Tallahassee, FL, 32306, USAPurpose: To report a case where the induction of macular edema with topical latanoprost coupled with in-office gas injection effectively sealed a persistent, chronic, macular hole. Observations: A 70-year-old, pseudophakic, patient presented with a stage three, chronic, macular hole (MH) and vision reduced to 20/200. The symptoms had been present for 18 months. Patient had surgery with pars plana vitrectomy (PPV), complete internal limiting membrane (ILM) peel to the arcades, 30% SF6 gas, and excellent face down positioning for five days. Two weeks after surgery the macular hole failed to close, and the edges of the hole were blunted with very little retinal edema and vision reduced to 20/400. The patient did not want to go back to the operating room. After informed consent, the patient was started on topical latanoprost 0.005% on the operative eye twice a day for six weeks. After latanoprost induction of cystoid macular edema (CME), the patient had 0.7 cc of pure C3F8 injected into the vitreous cavity in the office and was instructed to be face down for five days. Two weeks later the macular hole was closed with vision of 20/80. Last corrected vision eight months later was 20/50. Conclusions and Importance: The findings in this case suggest that induction of CME facilitated the closure of a chronic, persistent, macular hole with a simple gas injection in the office and face down positioning for five days.http://www.sciencedirect.com/science/article/pii/S2451993622003498Chronic macular holeLatanoprostCystoid macular edemaHydration
spellingShingle H Logan Brooks, Jr.
Cuneyt Ozkardes
Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole
American Journal of Ophthalmology Case Reports
Chronic macular hole
Latanoprost
Cystoid macular edema
Hydration
title Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole
title_full Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole
title_fullStr Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole
title_full_unstemmed Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole
title_short Intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed, chronic, macular hole
title_sort intentional use of topical latanoprost with resulting macular edema to help in the closure of a failed chronic macular hole
topic Chronic macular hole
Latanoprost
Cystoid macular edema
Hydration
url http://www.sciencedirect.com/science/article/pii/S2451993622003498
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