Xanthine Oxidoreductase-Mediated Superoxide Production Is Not Involved in the Age-Related Pathologies in <i>Sod1</i>-Deficient Mice

Xanthine Oxidoreductase-Mediated Superoxide Production Is Not Involved in the Age-Related Pathologies in <i>Sod1</i>-Deficient Mice

Reactive oxygen species (ROS) metabolism is regulated by the oxygen-mediated enzyme reaction and antioxidant mechanism within cells under physiological conditions. Xanthine oxidoreductase (XOR) exhibits two inter-convertible forms (xanthine oxidase (XO) and xanthine dehydrogenase (XDH)), depending o...

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Bibliographic Details
Main Authors: Shuichi Shibuya, Kenji Watanabe, Yusuke Ozawa, Takahiko Shimizu
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
superoxide
SOD1
xanthine oxidoreductase
aging
oxidative stress
Online Access:https://www.mdpi.com/1422-0067/22/7/3542

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