Macrophage migration inhibitory factor promoter polymorphisms are associated with disease activity in rheumatoid arthritis patients from Southern Mexico

Macrophage migration inhibitory factor promoter polymorphisms are associated with disease activity in rheumatoid arthritis patients from Southern Mexico

Abstract Background Macrophage migration inhibitory factor (MIF) is a cytokine capable of stimulating inflammatory cytokine and matrix metalloproteinase production from macrophages and synovial fibroblasts, which leads to persistent inflammation and bone degradation, two of the major pathological pr...

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Bibliographic Details
Main Authors: Guillermo Santoscoy‐Ascencio, Christian Johana Baños‐Hernández, José Eduardo Navarro‐Zarza, Jorge Hernández‐Bello, Richard Bucala, Andres López‐Quintero, Emmanuel Valdés‐Alvarado, Isela Parra‐Rojas, Berenice Illades‐Aguiar, José Francisco Muñoz‐Valle
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
DAS28
genetic susceptibility
MIF
polymorphisms
rheumatoid arthritis
Online Access:https://doi.org/10.1002/mgg3.1037

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