Differentiation and selection of hepatocyte precursors in suspension spheroid culture of transgenic murine embryonic stem cells.
Embryonic stem cell-derived hepatocyte precursor cells represent a promising model for clinical transplantations to diseased livers, as well as for establishment of in vitro systems for drug metabolism and toxicology investigations. This study aimed to establish an in vitro culture system for scalab...
Main Authors: | Elke Gabriel, Stephanie Schievenbusch, Eugen Kolossov, Jan G Hengstler, Tamara Rotshteyn, Heribert Bohlen, Dirk Nierhoff, Jürgen Hescheler, Irina Drobinskaya |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3454367?pdf=render |
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