Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report
Sertoli-Leydig cell tumours (SLCTs) are rare sex cord stromal neoplasms of ovary accounting for less than 0.5% of all ovarian tumours. These are found in women of all age groups (2-75 y), but are most common in reproductive age group with an average age of 25 y. Mostly these are unilateral, confin...
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JCDR Research and Publications Private Limited
2014-10-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/5014/9394_CE(Ra)_F(Sh)_PF1(PAK)_PFA(Sh).pdf |
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| author | Umesh Sidheshwar Kanade Sunita Sanjay Dantkale Rahul Ravindra Narkhede Rupali Ramrao Kurawar Shubhada Yadavrao Bansode |
| author_facet | Umesh Sidheshwar Kanade Sunita Sanjay Dantkale Rahul Ravindra Narkhede Rupali Ramrao Kurawar Shubhada Yadavrao Bansode |
| author_sort | Umesh Sidheshwar Kanade |
| collection | DOAJ |
| description | Sertoli-Leydig cell tumours (SLCTs) are rare sex cord stromal neoplasms of ovary accounting for less than 0.5% of all ovarian tumours.
These are found in women of all age groups (2-75 y), but are most common in reproductive age group with an average age of
25 y. Mostly these are unilateral, confined to ovaries and usually stage I at the time of clinical diagnosis. The common presenting
complaints in these patients are due to either mass occupying lesion (mostly pelviabdominal mass and/or pain) or hormonal production
(mostly androgen and more rarely oestrogen). Androgenic manifestations, seen in 80% of patients with SLCT, are virilism, hirsutism,
receding hairline, breast atrophy, clitoromegaly, acne, hoarseness of voice, etc. Estrogenic manifestations are precocious puberty,
abnormal uterine bleeding, abnormal vaginal bleeding, menstrual irregularities, generalised oedema, weight gain, breast hypertrophy,
endometrial hyperplasia, endometrial polyps and endometrial carcinoma. Histologically these are classified (WHO) as well-differentiated,
intermediately differentiated, poorly differentiated, with heterologous components and retiform type. Prognosis depends upon degree
of tumour differentiation (grading) and tumour extent (staging). We herein report an unusual case of SLCT of ovary with oestrogenic
manifestation of menorrhagia. |
| first_indexed | 2024-12-21T07:24:55Z |
| format | Article |
| id | doaj.art-9560ec4540224447b0a3106bcdee814e |
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| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-21T07:24:55Z |
| publishDate | 2014-10-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-9560ec4540224447b0a3106bcdee814e2022-12-21T19:11:42ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2014-10-01810FD18FD2010.7860/JCDR/2014/9394.5014Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case ReportUmesh Sidheshwar Kanade0Sunita Sanjay Dantkale1Rahul Ravindra Narkhede2Rupali Ramrao Kurawar3Shubhada Yadavrao Bansode4Assistant Professor, Department of Pathology, Government Medical College and Hospital Latur, India.Associate Professor, Department of Pathology, Government Medical College and Hospital Latur, India.Assistant Professor, Department of Pathology, Government Medical College and Hospital Latur, India.Junior Resident, Department of Pathology, Government Medical College and Hospital Latur, India.Assistant Professor, Department of Pathology, Government Medical College and Hospital Latur, India.Sertoli-Leydig cell tumours (SLCTs) are rare sex cord stromal neoplasms of ovary accounting for less than 0.5% of all ovarian tumours. These are found in women of all age groups (2-75 y), but are most common in reproductive age group with an average age of 25 y. Mostly these are unilateral, confined to ovaries and usually stage I at the time of clinical diagnosis. The common presenting complaints in these patients are due to either mass occupying lesion (mostly pelviabdominal mass and/or pain) or hormonal production (mostly androgen and more rarely oestrogen). Androgenic manifestations, seen in 80% of patients with SLCT, are virilism, hirsutism, receding hairline, breast atrophy, clitoromegaly, acne, hoarseness of voice, etc. Estrogenic manifestations are precocious puberty, abnormal uterine bleeding, abnormal vaginal bleeding, menstrual irregularities, generalised oedema, weight gain, breast hypertrophy, endometrial hyperplasia, endometrial polyps and endometrial carcinoma. Histologically these are classified (WHO) as well-differentiated, intermediately differentiated, poorly differentiated, with heterologous components and retiform type. Prognosis depends upon degree of tumour differentiation (grading) and tumour extent (staging). We herein report an unusual case of SLCT of ovary with oestrogenic manifestation of menorrhagia.https://jcdr.net/articles/PDF/5014/9394_CE(Ra)_F(Sh)_PF1(PAK)_PFA(Sh).pdfmenorrhagiasertoli-leydig cell tumoursex cord stromal tumour |
| spellingShingle | Umesh Sidheshwar Kanade Sunita Sanjay Dantkale Rahul Ravindra Narkhede Rupali Ramrao Kurawar Shubhada Yadavrao Bansode Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report Journal of Clinical and Diagnostic Research menorrhagia sertoli-leydig cell tumour sex cord stromal tumour |
| title | Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report |
| title_full | Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report |
| title_fullStr | Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report |
| title_full_unstemmed | Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report |
| title_short | Sertoli-Leydig Cell Tumour of Ovary with Menorrhagia: A Rare Case Report |
| title_sort | sertoli leydig cell tumour of ovary with menorrhagia a rare case report |
| topic | menorrhagia sertoli-leydig cell tumour sex cord stromal tumour |
| url | https://jcdr.net/articles/PDF/5014/9394_CE(Ra)_F(Sh)_PF1(PAK)_PFA(Sh).pdf |
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