Off-label prescriptions in diabetic foot
Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descr...
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Format: | Article |
Language: | English |
Published: |
Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)
2014-09-01
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Series: | Jornal Vascular Brasileiro |
Subjects: | |
Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192&lng=en&tlng=en |
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author | Luís Jesuíno de Oliveira Andrade Larissa Santos França Paulo Roberto Santana de Melo Marcelo Araújo |
author_facet | Luís Jesuíno de Oliveira Andrade Larissa Santos França Paulo Roberto Santana de Melo Marcelo Araújo |
author_sort | Luís Jesuíno de Oliveira Andrade |
collection | DOAJ |
description | Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance. |
first_indexed | 2024-12-21T22:01:44Z |
format | Article |
id | doaj.art-95610425e88c4dc8b22b12877bafe73e |
institution | Directory Open Access Journal |
issn | 1677-7301 |
language | English |
last_indexed | 2024-12-21T22:01:44Z |
publishDate | 2014-09-01 |
publisher | Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) |
record_format | Article |
series | Jornal Vascular Brasileiro |
spelling | doaj.art-95610425e88c4dc8b22b12877bafe73e2022-12-21T18:48:49ZengSociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)Jornal Vascular Brasileiro1677-73012014-09-0113319219710.1590/jvb.2014.025S1677-54492014000300192Off-label prescriptions in diabetic footLuís Jesuíno de Oliveira AndradeLarissa Santos FrançaPaulo Roberto Santana de MeloMarcelo AraújoPrescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192&lng=en&tlng=enuso off-labelpé diabéticodiabetes mellitus |
spellingShingle | Luís Jesuíno de Oliveira Andrade Larissa Santos França Paulo Roberto Santana de Melo Marcelo Araújo Off-label prescriptions in diabetic foot Jornal Vascular Brasileiro uso off-label pé diabético diabetes mellitus |
title | Off-label prescriptions in diabetic foot |
title_full | Off-label prescriptions in diabetic foot |
title_fullStr | Off-label prescriptions in diabetic foot |
title_full_unstemmed | Off-label prescriptions in diabetic foot |
title_short | Off-label prescriptions in diabetic foot |
title_sort | off label prescriptions in diabetic foot |
topic | uso off-label pé diabético diabetes mellitus |
url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192&lng=en&tlng=en |
work_keys_str_mv | AT luisjesuinodeoliveiraandrade offlabelprescriptionsindiabeticfoot AT larissasantosfranca offlabelprescriptionsindiabeticfoot AT paulorobertosantanademelo offlabelprescriptionsindiabeticfoot AT marceloaraujo offlabelprescriptionsindiabeticfoot |