Off-label prescriptions in diabetic foot

Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descr...

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Main Authors: Luís Jesuíno de Oliveira Andrade, Larissa Santos França, Paulo Roberto Santana de Melo, Marcelo Araújo
Format: Article
Language:English
Published: Sociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV) 2014-09-01
Series:Jornal Vascular Brasileiro
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192&lng=en&tlng=en
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author Luís Jesuíno de Oliveira Andrade
Larissa Santos França
Paulo Roberto Santana de Melo
Marcelo Araújo
author_facet Luís Jesuíno de Oliveira Andrade
Larissa Santos França
Paulo Roberto Santana de Melo
Marcelo Araújo
author_sort Luís Jesuíno de Oliveira Andrade
collection DOAJ
description Prescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance.
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spelling doaj.art-95610425e88c4dc8b22b12877bafe73e2022-12-21T18:48:49ZengSociedade Brasileira de Angiologia e de Cirurgia Vascular (SBACV)Jornal Vascular Brasileiro1677-73012014-09-0113319219710.1590/jvb.2014.025S1677-54492014000300192Off-label prescriptions in diabetic footLuís Jesuíno de Oliveira AndradeLarissa Santos FrançaPaulo Roberto Santana de MeloMarcelo AraújoPrescription of a drug outside of the indications for which it was originally approved by regulators is internationally known as "off-label" prescription. We describe off-label treatments for the diabetic foot reported in international scientific literature. This is a qualitative and descriptive bibliographical review based on the results of a search of the Medline international database. The criteria for review were publication between January 1985 and November 2013, and the MeSH (Medical Subject Heading) keywords "off-label use" OR "off-label" OR "off-label prescribing" plus "diabetic foot" were input on the search form. Nine studies were selected that contained information about off-label treatments for the diabetic foot. We conclude that the practice of off-label prescribing has potential benefits. In some situations an off-label prescription is the only treatment available for patients, either because a more targeted drug does not exist, or because other methods of treatment are ineffective or unavailable due to patient intolerance.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192&lng=en&tlng=enuso off-labelpé diabéticodiabetes mellitus
spellingShingle Luís Jesuíno de Oliveira Andrade
Larissa Santos França
Paulo Roberto Santana de Melo
Marcelo Araújo
Off-label prescriptions in diabetic foot
Jornal Vascular Brasileiro
uso off-label
pé diabético
diabetes mellitus
title Off-label prescriptions in diabetic foot
title_full Off-label prescriptions in diabetic foot
title_fullStr Off-label prescriptions in diabetic foot
title_full_unstemmed Off-label prescriptions in diabetic foot
title_short Off-label prescriptions in diabetic foot
title_sort off label prescriptions in diabetic foot
topic uso off-label
pé diabético
diabetes mellitus
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-54492014000300192&lng=en&tlng=en
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AT larissasantosfranca offlabelprescriptionsindiabeticfoot
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AT marceloaraujo offlabelprescriptionsindiabeticfoot