Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells.
SUMMARY:Reprogramming autologous adult cells to pluripotent cells allows for relatively safe cell replacement therapy. This can be achieved by nuclear transfer, cell fusion, or induced pluripotent stem cell technology However, the epigenetic memory of the cell is considered as a great challenge faci...
Main Authors: | Zaynab El-Gammal, Abdelrahman AlOkda, Sameh S Ali, Asmaa Reda, Sameh Magdeldin, Ragaa Mansour, Nagwa El-Badri |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0232759 |
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