Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews
Jixin Chen,1,2,* Aifeng Liu,1,2,* Qinxin Zhou,1,2 Weijie Yu,1,2 Tianci Guo,1,2 Yizhen Jia,1,2 Kun Yang,1,2 Puyu Niu,1,2 Huichuan Feng1,2 1Department of Orthopaedic Surgery, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, People’s Republ...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-11-01
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| Series: | International Journal of General Medicine |
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| Online Access: | https://www.dovepress.com/acupuncture-for-the-treatment-of-knee-osteoarthritis-an-overview-of-sy-peer-reviewed-fulltext-article-IJGM |
| _version_ | 1818741832636432384 |
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| author | Chen J Liu A Zhou Q Yu W Guo T Jia Y Yang K Niu P Feng H |
| author_facet | Chen J Liu A Zhou Q Yu W Guo T Jia Y Yang K Niu P Feng H |
| author_sort | Chen J |
| collection | DOAJ |
| description | Jixin Chen,1,2,* Aifeng Liu,1,2,* Qinxin Zhou,1,2 Weijie Yu,1,2 Tianci Guo,1,2 Yizhen Jia,1,2 Kun Yang,1,2 Puyu Niu,1,2 Huichuan Feng1,2 1Department of Orthopaedic Surgery, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, People’s Republic of China; 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, People’s Republic of China*These authors contributed equally to this workCorrespondence: Aifeng LiuDepartment of Orthopaedic Surgery, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, No. 88 Changling Road, Xiqing District, Tianjin, 300381, People’s Republic of ChinaTel +86-13803091533Email draifeng@163.comBackground: Acupuncture has been widely used in the clinical management of osteoarthritis of the knee (KOA). Many systematic reviews (SRs) and meta-analyses (MAs) have reported its effectiveness in relieving pain. This overview aimed to summarize SRs and MAs on the effectiveness and safety of acupuncture for KOA and evaluate their methodological and evidence quality of the included SRs and MAs.Methods: We conducted a comprehensive literature search for SRs and MAs in four Chinese and four international databases from their inception until August 2021. Two researchers independently searched the reviews, extracted the data, and cross-checked the data. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR 2) tool was used to evaluate the methodological quality of the included SRs and MAs. The Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) system was used to assess the quality of evidence for the outcomes of the included SRs and MAs.Results: A total of 14 SRs and MAs were included. The evaluation results of the AMSTAR 2 tool showed that the methodological quality of all the 14 SRs and MAs was critically low. The principal causes are the lack of a pre-registration proposal and a list of excluded studies and justify the exclusions, the report on the sources of funding, and the reasons for the study designs for inclusion. The results of the GRADE evaluation showed 25 of 46 outcomes were very low-level evidence. Seventeen were of low level, four were of moderate level and none were of high level. Most outcomes were downgraded in quality of evidence mainly because of publication bias and imprecision.Conclusion: The existing evidence suggests that acupuncture seems to be an effective and safe therapy for KOA. However, the deficiencies in the methodological quality and quality of evidence of the included SRs/MAs have limited the reliability of the conclusions. Therefore, further rigorous and comprehensive studies are warranted to verify the effectiveness and safety of acupuncture in KOA.Keywords: acupuncture, knee osteoarthritis, overview, AMSTAR 2, GRADE, systematic review |
| first_indexed | 2024-12-18T02:02:53Z |
| format | Article |
| id | doaj.art-9564fe0b60024c77b3838f02082ab320 |
| institution | Directory Open Access Journal |
| issn | 1178-7074 |
| language | English |
| last_indexed | 2024-12-18T02:02:53Z |
| publishDate | 2021-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of General Medicine |
| spelling | doaj.art-9564fe0b60024c77b3838f02082ab3202022-12-21T21:24:43ZengDove Medical PressInternational Journal of General Medicine1178-70742021-11-01Volume 148481849470714Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic ReviewsChen JLiu AZhou QYu WGuo TJia YYang KNiu PFeng HJixin Chen,1,2,* Aifeng Liu,1,2,* Qinxin Zhou,1,2 Weijie Yu,1,2 Tianci Guo,1,2 Yizhen Jia,1,2 Kun Yang,1,2 Puyu Niu,1,2 Huichuan Feng1,2 1Department of Orthopaedic Surgery, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, 300381, People’s Republic of China; 2National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, 300381, People’s Republic of China*These authors contributed equally to this workCorrespondence: Aifeng LiuDepartment of Orthopaedic Surgery, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, No. 88 Changling Road, Xiqing District, Tianjin, 300381, People’s Republic of ChinaTel +86-13803091533Email draifeng@163.comBackground: Acupuncture has been widely used in the clinical management of osteoarthritis of the knee (KOA). Many systematic reviews (SRs) and meta-analyses (MAs) have reported its effectiveness in relieving pain. This overview aimed to summarize SRs and MAs on the effectiveness and safety of acupuncture for KOA and evaluate their methodological and evidence quality of the included SRs and MAs.Methods: We conducted a comprehensive literature search for SRs and MAs in four Chinese and four international databases from their inception until August 2021. Two researchers independently searched the reviews, extracted the data, and cross-checked the data. The Assessing the Methodological Quality of Systematic Reviews 2 (AMSTAR 2) tool was used to evaluate the methodological quality of the included SRs and MAs. The Grades of Recommendations, Assessment, Development, and Evaluation (GRADE) system was used to assess the quality of evidence for the outcomes of the included SRs and MAs.Results: A total of 14 SRs and MAs were included. The evaluation results of the AMSTAR 2 tool showed that the methodological quality of all the 14 SRs and MAs was critically low. The principal causes are the lack of a pre-registration proposal and a list of excluded studies and justify the exclusions, the report on the sources of funding, and the reasons for the study designs for inclusion. The results of the GRADE evaluation showed 25 of 46 outcomes were very low-level evidence. Seventeen were of low level, four were of moderate level and none were of high level. Most outcomes were downgraded in quality of evidence mainly because of publication bias and imprecision.Conclusion: The existing evidence suggests that acupuncture seems to be an effective and safe therapy for KOA. However, the deficiencies in the methodological quality and quality of evidence of the included SRs/MAs have limited the reliability of the conclusions. Therefore, further rigorous and comprehensive studies are warranted to verify the effectiveness and safety of acupuncture in KOA.Keywords: acupuncture, knee osteoarthritis, overview, AMSTAR 2, GRADE, systematic reviewhttps://www.dovepress.com/acupuncture-for-the-treatment-of-knee-osteoarthritis-an-overview-of-sy-peer-reviewed-fulltext-article-IJGMacupunctureknee osteoarthritisoverviewamstar 2gradesystematic review |
| spellingShingle | Chen J Liu A Zhou Q Yu W Guo T Jia Y Yang K Niu P Feng H Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews International Journal of General Medicine acupuncture knee osteoarthritis overview amstar 2 grade systematic review |
| title | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
| title_full | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
| title_fullStr | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
| title_full_unstemmed | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
| title_short | Acupuncture for the Treatment of Knee Osteoarthritis: An Overview of Systematic Reviews |
| title_sort | acupuncture for the treatment of knee osteoarthritis an overview of systematic reviews |
| topic | acupuncture knee osteoarthritis overview amstar 2 grade systematic review |
| url | https://www.dovepress.com/acupuncture-for-the-treatment-of-knee-osteoarthritis-an-overview-of-sy-peer-reviewed-fulltext-article-IJGM |
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