Complexing Protein-Free Botulinum Neurotoxin A Formulations: Implications of Excipients for Immunogenicity

Complexing Protein-Free Botulinum Neurotoxin A Formulations: Implications of Excipients for Immunogenicity

The formation of neutralizing antibodies is a growing concern in the use of botulinum neurotoxin A (BoNT/A) as it may result in secondary treatment failure. Differences in the immunogenicity of BoNT/A formulations have been attributed to the presence of pharmacologically unnecessary bacterial compon...

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Bibliographic Details
Main Authors: Michael Uwe Martin, Juergen Frevert, Clifton Ming Tay
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Toxins
Subjects:
botulinum neurotoxin A
Coretox<sup>®</sup>
daxibotulinumtoxinA
excipients
immunogenicity
immunoresistance
Online Access:https://www.mdpi.com/2072-6651/16/2/101

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