Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis
This study investigated the surface properties, biocompatibility, and antifungal activity against <i>Candida albicans</i> of a denture-relining material coated with zinc-bound phosphate-based glass. First, zinc-bound phosphate-based glass was fabricated. A polymerized denture-relining di...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/17/3048 |
| _version_ | 1797493922963914752 |
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| author | Sang-Hwan Oh Yun-Sook Jung Myung-Jin Lee |
| author_facet | Sang-Hwan Oh Yun-Sook Jung Myung-Jin Lee |
| author_sort | Sang-Hwan Oh |
| collection | DOAJ |
| description | This study investigated the surface properties, biocompatibility, and antifungal activity against <i>Candida albicans</i> of a denture-relining material coated with zinc-bound phosphate-based glass. First, zinc-bound phosphate-based glass was fabricated. A polymerized denture-relining disk was coated with zinc-bound phosphate-based glass (2%, 4%, and 6%). The surface properties of the control and experimental groups were measured, including the wettability, microhardness, color difference, and gloss. The biocompatibility was evaluated using the MTT assay according to ISO 10993-5. The antifungal activity was investigated by counting the number of colony-forming units of <i>Candida albicans</i>. The results were analyzed using a one-way ANOVA and Tukey’s test (<i>p</i> = 0.05). The results of this study indicate that, despite the antimicrobial effect of zinc-bound phosphate-based glass, a coated denture-relining material does not degrade the surface properties and biocompatibility. Therefore, this novel material is considered promising for use as a dental material with antimicrobial properties that can potentially prevent denture stomatitis. |
| first_indexed | 2024-03-10T01:26:56Z |
| format | Article |
| id | doaj.art-956b66ec6baf493f9060a08c470a6d93 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-10T01:26:56Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-956b66ec6baf493f9060a08c470a6d932023-11-23T13:50:00ZengMDPI AGNanomaterials2079-49912022-09-011217304810.3390/nano12173048Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture StomatitisSang-Hwan Oh0Yun-Sook Jung1Myung-Jin Lee2Department of Dental Hygiene, Konyang University, Daejeon 35365, KoreaDepartment of Dental Hygiene, College of Science & Technology, Kyungpook National University, Sangju 37224, KoreaDepartment of Dental Hygiene, Division of Health Science, Baekseok University, Cheonan 31065, KoreaThis study investigated the surface properties, biocompatibility, and antifungal activity against <i>Candida albicans</i> of a denture-relining material coated with zinc-bound phosphate-based glass. First, zinc-bound phosphate-based glass was fabricated. A polymerized denture-relining disk was coated with zinc-bound phosphate-based glass (2%, 4%, and 6%). The surface properties of the control and experimental groups were measured, including the wettability, microhardness, color difference, and gloss. The biocompatibility was evaluated using the MTT assay according to ISO 10993-5. The antifungal activity was investigated by counting the number of colony-forming units of <i>Candida albicans</i>. The results were analyzed using a one-way ANOVA and Tukey’s test (<i>p</i> = 0.05). The results of this study indicate that, despite the antimicrobial effect of zinc-bound phosphate-based glass, a coated denture-relining material does not degrade the surface properties and biocompatibility. Therefore, this novel material is considered promising for use as a dental material with antimicrobial properties that can potentially prevent denture stomatitis.https://www.mdpi.com/2079-4991/12/17/3048antifungal efficacybiocompatibility<i>Candida albicans</i>dental materialssurface characterizationzinc-bound phosphate-based glass |
| spellingShingle | Sang-Hwan Oh Yun-Sook Jung Myung-Jin Lee Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis Nanomaterials antifungal efficacy biocompatibility <i>Candida albicans</i> dental materials surface characterization zinc-bound phosphate-based glass |
| title | Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis |
| title_full | Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis |
| title_fullStr | Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis |
| title_full_unstemmed | Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis |
| title_short | Assessment of Zinc-Bound Phosphate-Based Glass-Coated Denture-Relining Material with Antifungal Efficacy for Inhibiting Denture Stomatitis |
| title_sort | assessment of zinc bound phosphate based glass coated denture relining material with antifungal efficacy for inhibiting denture stomatitis |
| topic | antifungal efficacy biocompatibility <i>Candida albicans</i> dental materials surface characterization zinc-bound phosphate-based glass |
| url | https://www.mdpi.com/2079-4991/12/17/3048 |
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