Optimization of cancer immunotherapy through pyroptosis: A pyroptosis-related signature predicts survival benefit and potential synergy for immunotherapy in glioma

Optimization of cancer immunotherapy through pyroptosis: A pyroptosis-related signature predicts survival benefit and potential synergy for immunotherapy in glioma

BackgroundPyroptosis is a critical type of programmed cell death that is strongly associated with the regulation of tumor and immune cell functions. However, the role of pyroptosis in tumor progression and remodeling of the tumor microenvironment in gliomas has not been extensively studied. Thus, in...

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Bibliographic Details
Main Authors: Yu Zeng, Yonghua Cai, Peng Chai, Yangqi Mao, Yanwen Chen, Li Wang, Kunlin Zeng, Ziling Zhan, Yuxin Xie, Cuiying Li, Hongchao Zhan, Liqian Zhao, Xiaoxia Chen, Xiaoxia Zhu, Yu Liu, Ming Chen, Ye Song, Aidong Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
glioma
pyroptosis
prognosis
tumor-associated microenvironment
immunotherapy
small molecular inhibitor
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.961933/full

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