Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities
Respiratory disease continues to be the major cause of mortality in feedyard cattle, with bronchopneumonia (BP) and acute interstitial pneumonia (AIP) as the two most common syndromes. Recent studies described a combination of these pathological lesions with the presence of AIP in the caudodorsal lu...
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| Format: | Article |
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MDPI AG
2023-08-01
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| Series: | Veterinary Sciences |
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| Online Access: | https://www.mdpi.com/2306-7381/10/8/522 |
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| author | Eduarda M. Bortoluzzi Brad J. White Paige H. Schmidt Maddie R. Mancke Rachel E. Brown Makenna Jensen Phillip A. Lancaster Robert L. Larson |
| author_facet | Eduarda M. Bortoluzzi Brad J. White Paige H. Schmidt Maddie R. Mancke Rachel E. Brown Makenna Jensen Phillip A. Lancaster Robert L. Larson |
| author_sort | Eduarda M. Bortoluzzi |
| collection | DOAJ |
| description | Respiratory disease continues to be the major cause of mortality in feedyard cattle, with bronchopneumonia (BP) and acute interstitial pneumonia (AIP) as the two most common syndromes. Recent studies described a combination of these pathological lesions with the presence of AIP in the caudodorsal lungs and BP in the cranioventral lungs of necropsied cattle. This pulmonary pathology has been described as bronchopneumonia with an interstitial pneumonia (BIP). The epidemiological characteristics of BIP in U.S. feedyard cattle are yet to be described. This study’s objectives were to describe the agreement between feedyard clinical and necropsy gross diagnosis and to characterize epidemiological factors associated with four gross pulmonary diagnoses (AIP, BIP, BP, and Normal pulmonary tissue) observed during feedyard cattle necropsies. Systemic necropsies were performed at six feedyards in U.S. high plains region, and gross pulmonary diagnoses were established. Historical data were added to the dataset, including sex, days on feed at death (DOFDEATH), arrival weight, treatment count, and feedyard diagnosis. Generalized linear models were used to evaluate epidemiological factors associated with the probability of each pulmonary pathology. Comparing feedyard clinical diagnosis with gross pathological diagnosis revealed relatively low agreement and the frequency of agreement varied by diagnosis. The likelihood of AIP at necropsy was higher for heifers than steers and in the 100–150 DOFDEATH category compared with the 0–50 DOFDEATH (<i>p</i> = 0.05). The likelihood of BIP increased after the first treatment, whereas the DOFDEATH 0–50 category had a lower likelihood compared with the 150–200 category (<i>p</i> = 0.05). These findings highlight the importance of necropsy for final diagnosis and can aid the development of future diagnosis and therapeutic protocols for pulmonary diseases. |
| first_indexed | 2024-03-10T23:30:50Z |
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| institution | Directory Open Access Journal |
| issn | 2306-7381 |
| language | English |
| last_indexed | 2024-03-10T23:30:50Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Veterinary Sciences |
| spelling | doaj.art-956da946850f4747a53fad6cf83dfba82023-11-19T03:19:09ZengMDPI AGVeterinary Sciences2306-73812023-08-0110852210.3390/vetsci10080522Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard MortalitiesEduarda M. Bortoluzzi0Brad J. White1Paige H. Schmidt2Maddie R. Mancke3Rachel E. Brown4Makenna Jensen5Phillip A. Lancaster6Robert L. Larson7Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USABeef Cattle Institute, Kansas State University, Manhattan, KS 66506, USARespiratory disease continues to be the major cause of mortality in feedyard cattle, with bronchopneumonia (BP) and acute interstitial pneumonia (AIP) as the two most common syndromes. Recent studies described a combination of these pathological lesions with the presence of AIP in the caudodorsal lungs and BP in the cranioventral lungs of necropsied cattle. This pulmonary pathology has been described as bronchopneumonia with an interstitial pneumonia (BIP). The epidemiological characteristics of BIP in U.S. feedyard cattle are yet to be described. This study’s objectives were to describe the agreement between feedyard clinical and necropsy gross diagnosis and to characterize epidemiological factors associated with four gross pulmonary diagnoses (AIP, BIP, BP, and Normal pulmonary tissue) observed during feedyard cattle necropsies. Systemic necropsies were performed at six feedyards in U.S. high plains region, and gross pulmonary diagnoses were established. Historical data were added to the dataset, including sex, days on feed at death (DOFDEATH), arrival weight, treatment count, and feedyard diagnosis. Generalized linear models were used to evaluate epidemiological factors associated with the probability of each pulmonary pathology. Comparing feedyard clinical diagnosis with gross pathological diagnosis revealed relatively low agreement and the frequency of agreement varied by diagnosis. The likelihood of AIP at necropsy was higher for heifers than steers and in the 100–150 DOFDEATH category compared with the 0–50 DOFDEATH (<i>p</i> = 0.05). The likelihood of BIP increased after the first treatment, whereas the DOFDEATH 0–50 category had a lower likelihood compared with the 150–200 category (<i>p</i> = 0.05). These findings highlight the importance of necropsy for final diagnosis and can aid the development of future diagnosis and therapeutic protocols for pulmonary diseases.https://www.mdpi.com/2306-7381/10/8/522acute interstitial pneumoniabronchopneumonia with an interstitial pneumoniabronchopneumoniaepidemiologyfeedyard cattlebovine respiratory disease (BRD) |
| spellingShingle | Eduarda M. Bortoluzzi Brad J. White Paige H. Schmidt Maddie R. Mancke Rachel E. Brown Makenna Jensen Phillip A. Lancaster Robert L. Larson Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities Veterinary Sciences acute interstitial pneumonia bronchopneumonia with an interstitial pneumonia bronchopneumonia epidemiology feedyard cattle bovine respiratory disease (BRD) |
| title | Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities |
| title_full | Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities |
| title_fullStr | Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities |
| title_full_unstemmed | Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities |
| title_short | Epidemiological Factors Associated with Gross Diagnosis of Pulmonary Pathology in Feedyard Mortalities |
| title_sort | epidemiological factors associated with gross diagnosis of pulmonary pathology in feedyard mortalities |
| topic | acute interstitial pneumonia bronchopneumonia with an interstitial pneumonia bronchopneumonia epidemiology feedyard cattle bovine respiratory disease (BRD) |
| url | https://www.mdpi.com/2306-7381/10/8/522 |
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