Pharmaceutical Coating and Its Different Approaches, a Review
Coating the solid dosage form, such as tablets, is considered common, but it is a critical process that provides different characteristics to tablets. It increases the value of solid dosage form, administered orally, and thus meets diverse clinical requirements. As tablet coating is a process driven...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | Polymers |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4360/14/16/3318 |
| _version_ | 1797442517021491200 |
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| author | Ahmad Salawi |
| author_facet | Ahmad Salawi |
| author_sort | Ahmad Salawi |
| collection | DOAJ |
| description | Coating the solid dosage form, such as tablets, is considered common, but it is a critical process that provides different characteristics to tablets. It increases the value of solid dosage form, administered orally, and thus meets diverse clinical requirements. As tablet coating is a process driven by technology, it relies on advancements in coating techniques, equipment used for the coating process, evaluation of coated tablets, and coated material used. Although different techniques were employed for coating purposes, which may be based on the use of solvents or solvent-free, each of the methods used has its advantages and disadvantages, and the techniques need continued modification too. During the process of film coating, several inter-and intra-batch uniformity of coated material on the tablets is considered a critical point that ensures the worth of the final product, particularly for those drugs that contain an active medicament in the coating layer. Meanwhile, computational modeling and experimental evaluation were actively used to predict the impact of the operational parameters on the final product quality and optimize the variables in tablet coating. The efforts produced by computational modeling or experimental evaluation not only save cost in optimizing the coating process but also saves time. This review delivers a brief review on film coating in solid dosage form, which includes tablets, with a focus on the polymers and processes used in the coating. At the end, some pharmaceutical applications were also discussed. |
| first_indexed | 2024-03-09T12:43:00Z |
| format | Article |
| id | doaj.art-956e17a2bb3c4789b3069293d514ec89 |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-09T12:43:00Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-956e17a2bb3c4789b3069293d514ec892023-11-30T22:15:21ZengMDPI AGPolymers2073-43602022-08-011416331810.3390/polym14163318Pharmaceutical Coating and Its Different Approaches, a ReviewAhmad Salawi0Department of Pharmaceutics, College of Pharmacy, Jazan University, Jazan 45142, Saudi ArabiaCoating the solid dosage form, such as tablets, is considered common, but it is a critical process that provides different characteristics to tablets. It increases the value of solid dosage form, administered orally, and thus meets diverse clinical requirements. As tablet coating is a process driven by technology, it relies on advancements in coating techniques, equipment used for the coating process, evaluation of coated tablets, and coated material used. Although different techniques were employed for coating purposes, which may be based on the use of solvents or solvent-free, each of the methods used has its advantages and disadvantages, and the techniques need continued modification too. During the process of film coating, several inter-and intra-batch uniformity of coated material on the tablets is considered a critical point that ensures the worth of the final product, particularly for those drugs that contain an active medicament in the coating layer. Meanwhile, computational modeling and experimental evaluation were actively used to predict the impact of the operational parameters on the final product quality and optimize the variables in tablet coating. The efforts produced by computational modeling or experimental evaluation not only save cost in optimizing the coating process but also saves time. This review delivers a brief review on film coating in solid dosage form, which includes tablets, with a focus on the polymers and processes used in the coating. At the end, some pharmaceutical applications were also discussed.https://www.mdpi.com/2073-4360/14/16/3318solid dosage formuniformity in coating processtabletspolymersand film coating |
| spellingShingle | Ahmad Salawi Pharmaceutical Coating and Its Different Approaches, a Review Polymers solid dosage form uniformity in coating process tablets polymers and film coating |
| title | Pharmaceutical Coating and Its Different Approaches, a Review |
| title_full | Pharmaceutical Coating and Its Different Approaches, a Review |
| title_fullStr | Pharmaceutical Coating and Its Different Approaches, a Review |
| title_full_unstemmed | Pharmaceutical Coating and Its Different Approaches, a Review |
| title_short | Pharmaceutical Coating and Its Different Approaches, a Review |
| title_sort | pharmaceutical coating and its different approaches a review |
| topic | solid dosage form uniformity in coating process tablets polymers and film coating |
| url | https://www.mdpi.com/2073-4360/14/16/3318 |
| work_keys_str_mv | AT ahmadsalawi pharmaceuticalcoatinganditsdifferentapproachesareview |