Targeted Therapy in Metastatic Bladder Cancer: Present Status and Future Directions
The recommended treatment for metastatic urothelial carcinoma (mUC) patients is platinum-based chemotherapy. Although initial response rates are moderate, the vast majority of patients experience a relapse due to chemoresistance and eventually succumb to their disease. Furthermore, platinum-based ch...
Main Authors: | Mathijs Scholtes, Maryam Akbarzadeh, Ellen Zwarthoff, Joost Boormans, Tokameh Mahmoudi, Tahlita Zuiverloon |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-10-01
|
Series: | Applied Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3417/10/20/7102 |
Similar Items
-
Role of Bladder Cancer Metabolic Reprogramming in the Effectiveness of Immunotherapy
by: Mathijs P. Scholtes, et al.
Published: (2021-01-01) -
Role of tyrosine kinases in bladder cancer progression: an overview
by: Amir Sadra Zangouei, et al.
Published: (2020-08-01) -
Biomarker-Oriented Therapy in Bladder and Renal Cancer
by: Mathijs P. Scholtes, et al.
Published: (2021-03-01) -
Anti-Metastatic Effect of Pyruvate Dehydrogenase Kinase 4 Inhibition in Bladder Cancer via the ERK, SRC, and JNK Pathways
by: Eun Hye Lee, et al.
Published: (2022-10-01) -
Computational Characterization of Membrane Proteins as Anticancer Targets: Current Challenges and Opportunities
by: Marina Gorostiola González, et al.
Published: (2024-03-01)