Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis
Abstract Background Arteriovenous (AV) hemodialysis access creation is recommended by international guidelines as the preferred method of hemodialysis access. However, most AV access sites will require revision to maintain patency. Although several treatment options exist, many have not been directl...
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| Format: | Article |
| Language: | English |
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BMC
2020-08-01
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| Series: | Systematic Reviews |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s13643-020-01435-1 |
| _version_ | 1818317308045557760 |
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| author | Mark Rockley Sudhir Nagpal Ashish Gupta Derek J. Roberts |
| author_facet | Mark Rockley Sudhir Nagpal Ashish Gupta Derek J. Roberts |
| author_sort | Mark Rockley |
| collection | DOAJ |
| description | Abstract Background Arteriovenous (AV) hemodialysis access creation is recommended by international guidelines as the preferred method of hemodialysis access. However, most AV access sites will require revision to maintain patency. Although several treatment options exist, many have not been directly compared. We intend to compare the relative effectiveness of methods to maintain post-intervention primary patency of failing AV access. Methods We will search EMBASE, MEDLINE, CENTRAL, trial registries, the grey literature, and ancestry and citation search from January 1977 to present, for randomized controlled trials comparing interventions to maintain primary patency of AV access. Two investigators will independently and blindly review all identified citations and extract data from included studies. The primary outcome is the primary patency 6 months after intervention. Secondary outcomes include immediate technical and functional success, reinterventions, patency, and mortality. Risk of bias, subgroup analyses, and sensitivity analyses are planned. Discussion There are a number of treatment modalities for the management of failing AV access. However, most modalities have only been directly compared with plain old balloon angioplasty, and currently synthesized evidence focuses on individual pairwise comparisons. In light of the lack of comprehensively synthesized evidence and clinical equipoise, our study intends to synthesize currently available evidence though it is unclear which treatment modality is most effective. Systematic review registration PROSPERO ID CRD42020148224 |
| first_indexed | 2024-12-13T09:35:15Z |
| format | Article |
| id | doaj.art-9572ffa994b84686b7e5494d8fefcc41 |
| institution | Directory Open Access Journal |
| issn | 2046-4053 |
| language | English |
| last_indexed | 2024-12-13T09:35:15Z |
| publishDate | 2020-08-01 |
| publisher | BMC |
| record_format | Article |
| series | Systematic Reviews |
| spelling | doaj.art-9572ffa994b84686b7e5494d8fefcc412022-12-21T23:52:23ZengBMCSystematic Reviews2046-40532020-08-01911910.1186/s13643-020-01435-1Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysisMark Rockley0Sudhir Nagpal1Ashish Gupta2Derek J. Roberts3University of OttawaUniversity of OttawaUniversity of OttawaUniversity of OttawaAbstract Background Arteriovenous (AV) hemodialysis access creation is recommended by international guidelines as the preferred method of hemodialysis access. However, most AV access sites will require revision to maintain patency. Although several treatment options exist, many have not been directly compared. We intend to compare the relative effectiveness of methods to maintain post-intervention primary patency of failing AV access. Methods We will search EMBASE, MEDLINE, CENTRAL, trial registries, the grey literature, and ancestry and citation search from January 1977 to present, for randomized controlled trials comparing interventions to maintain primary patency of AV access. Two investigators will independently and blindly review all identified citations and extract data from included studies. The primary outcome is the primary patency 6 months after intervention. Secondary outcomes include immediate technical and functional success, reinterventions, patency, and mortality. Risk of bias, subgroup analyses, and sensitivity analyses are planned. Discussion There are a number of treatment modalities for the management of failing AV access. However, most modalities have only been directly compared with plain old balloon angioplasty, and currently synthesized evidence focuses on individual pairwise comparisons. In light of the lack of comprehensively synthesized evidence and clinical equipoise, our study intends to synthesize currently available evidence though it is unclear which treatment modality is most effective. Systematic review registration PROSPERO ID CRD42020148224http://link.springer.com/article/10.1186/s13643-020-01435-1AngioplastyStentHemodialysis accessArteriovenousPatency |
| spellingShingle | Mark Rockley Sudhir Nagpal Ashish Gupta Derek J. Roberts Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis Systematic Reviews Angioplasty Stent Hemodialysis access Arteriovenous Patency |
| title | Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis |
| title_full | Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis |
| title_fullStr | Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis |
| title_full_unstemmed | Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis |
| title_short | Efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency: protocol for a systematic review and network meta-analysis |
| title_sort | efficacy and safety of secondary procedures for maintaining arteriovenous hemodialysis access patency protocol for a systematic review and network meta analysis |
| topic | Angioplasty Stent Hemodialysis access Arteriovenous Patency |
| url | http://link.springer.com/article/10.1186/s13643-020-01435-1 |
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