| Summary: | The article presents the results of population-based study of a representative sample of the population of one of the districts of Novosibirsk, conducted in 2013–2014. A total of 749 people of both sexes (43 % men) aged 25–45 years were examined. The response rate was 38 %. The program included a survey questionnaire on smoking and socio-economic factors (education, marital status, employment). Measurement of blood pressure, anthropometric parameters, serum cotinine, total cholesterol and its fractions, blood glucose were conducted. The high prevalence of smoking among men (46 %) and women (24 %) revealed. Associations of smoking with cardiometabolic risk factors such as hypertension, hyperglycemia and hypo-HDL-C were received. On the subsample (273 people) using the verification of the questionnaire on smoking by serum cotinine 4–6 % false answers were found. Marked increasing in female smoking and decreasing in male smoking in the past 20 years in Novosibirsk were revealed.
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