Single-Cell NGS-Based Analysis of Copy Number Alterations Reveals New Insights in Circulating Tumor Cells Persistence in Early-Stage Breast Cancer

Single-Cell NGS-Based Analysis of Copy Number Alterations Reveals New Insights in Circulating Tumor Cells Persistence in Early-Stage Breast Cancer

Circulating tumor cells (CTCs) are a rare population of cells representing a key player in the metastatic cascade. They are recognized as a validated tool for the identification of patients with a higher risk of relapse, including those diagnosed with breast cancer (BC). However, CTCs are characteri...

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Bibliographic Details
Main Authors: Tania Rossi, Giulia Gallerani, Davide Angeli, Claudia Cocchi, Erika Bandini, Pietro Fici, Michele Gaudio, Giovanni Martinelli, Andrea Rocca, Roberta Maltoni, Francesco Fabbri
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
CTCs
breast cancer
single-cell analysis
CNA
NGS
liquid biopsy
Online Access:https://www.mdpi.com/2072-6694/12/9/2490

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