Emerging systemic therapy options beyond CDK4/6 inhibitors for hormone receptor-positive HER2-negative advanced breast cancer

Abstract Endocrine therapy (ET) with cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) is currently the standard first-line treatment for most patients with hormone receptor (HR) positive, human epidermal growth factor receptor (HER2) negative advanced breast cancer. However, resistance to ET and CDK4...

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Bibliographic Details
Main Authors: Jun Ma, Jack Junjie Chan, Ching Han Toh, Yoon-Sim Yap
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-023-00578-3