Emerging systemic therapy options beyond CDK4/6 inhibitors for hormone receptor-positive HER2-negative advanced breast cancer
Abstract Endocrine therapy (ET) with cyclin-dependent kinase 4/6 inhibitor (CDK4/6i) is currently the standard first-line treatment for most patients with hormone receptor (HR) positive, human epidermal growth factor receptor (HER2) negative advanced breast cancer. However, resistance to ET and CDK4...
Main Authors: | Jun Ma, Jack Junjie Chan, Ching Han Toh, Yoon-Sim Yap |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
|
Series: | npj Breast Cancer |
Online Access: | https://doi.org/10.1038/s41523-023-00578-3 |
Similar Items
-
CDK4/6 inhibitors in breast cancer: beyond hormone receptor-positive HER2-negative disease
by: Adriana Matutino, et al.
Published: (2018-12-01) -
Circulating Biomarkers of CDK4/6 Inhibitors Response in Hormone Receptor Positive and HER2 Negative Breast Cancer
by: Ilenia Migliaccio, et al.
Published: (2021-05-01) -
The dilemma of selecting a first line CDK4/6 inhibitor for hormone receptor-positive/HER2-negative metastatic breast cancer
by: Albert Grinshpun, et al.
Published: (2023-03-01) -
Treatment options for patients with hormone receptor-positive, HER2-negative advanced-stage breast cancer: maintaining cyclin-dependent kinase 4/6 inhibitors beyond progression
by: Malek Horani, et al.
Published: (2023-10-01) -
Peripheral blood lymphocytes predict clinical outcomes in hormone receptor-positive HER2-negative advanced breast cancer patients treated with CDK4/6 inhibitors
by: Emma Zattarin, et al.
Published: (2023-12-01)