Activation of Intracellular Complement in Lungs of Patients With Severe COVID-19 Disease Decreases T-Cell Activity in the Lungs

Activation of Intracellular Complement in Lungs of Patients With Severe COVID-19 Disease Decreases T-Cell Activity in the Lungs

A novel coronavirus, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), arose late in 2019, with disease pathology ranging from asymptomatic to severe respiratory distress with multi-organ failure requiring mechanical ventilator support. It has been found that SARS-CoV-2 infection drives...

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Bibliographic Details
Main Authors: Mark C. Howell, Ryan Green, Andrew R. McGill, Roukiah M. Kahlil, Rinku Dutta, Shyam S. Mohapatra, Subhra Mohapatra
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-11-01
Series:Frontiers in Immunology
Subjects:
bioinformatics
T-cells
complement
severe COVID-19 disease
lungs
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.700705/full

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