Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata
The current study uses an economical and eco friendly method to produce gold (Au) nanoparticles (NPs) using Polygala elongata leaf (PEL) extract as a reducing and stabilizing agent. The synthesized materials were characterized using a range of methods, including as BET analysis, TEM-SAED, FT-IR, UV–...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-05-01
|
| Series: | Journal of King Saud University: Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1018364724000703 |
| _version_ | 1827284855494279168 |
|---|---|
| author | M. Elangovan Murali Santhoshkumar Kumar Selvaraj Kuppusamy Sathishkumar Manimaran Kumar Mukesh Kumar Dharmalingam Jothinathan Mansour K. Gatasheh Gajendra Kumar Gaurav K. Rajesh |
| author_facet | M. Elangovan Murali Santhoshkumar Kumar Selvaraj Kuppusamy Sathishkumar Manimaran Kumar Mukesh Kumar Dharmalingam Jothinathan Mansour K. Gatasheh Gajendra Kumar Gaurav K. Rajesh |
| author_sort | M. Elangovan |
| collection | DOAJ |
| description | The current study uses an economical and eco friendly method to produce gold (Au) nanoparticles (NPs) using Polygala elongata leaf (PEL) extract as a reducing and stabilizing agent. The synthesized materials were characterized using a range of methods, including as BET analysis, TEM-SAED, FT-IR, UV–Vis, and XRD. Biogenic AuNPs' spherical form was shown by SEM and TEM investigations, which also showed that the particles' size range was 10–20 nm, their distribution was homogeneous, and there observed minimal aggregation. The production of biogenic AuNPs was confirmed by the observation of a surface plasmon resonance peak in the absorption spectra, which was detected at 540 nm. Additionally, studies were conducted on the catalytic, cytotoxic, antioxidant, and anticancer characteristics of biogenic AuNPs. The biogenic AuNPs exhibited adaptable applications as a heterogeneous catalyst, achieving percentage degradations of 73 % and 88 % under UV light irradiation, particularly in catalyzing the reduction of Methylene Blue (MeB). Furthermore, the antioxidant properties were evaluated using DPPH free radical scavenging assay in regarding rutin, a widely used antioxidant. With a cytotoxicity value of 500 µg/ml, the produced AuNPs had a strong dose-dependent inhibitory effect on the development of the lung cancer cell line (A549). Therefore, biogenic AuNPs hold potential applications across various research domains, spanning biological and industrial sectors, as well as in the removal of harmful contaminants in water purification. |
| first_indexed | 2024-04-24T10:05:26Z |
| format | Article |
| id | doaj.art-958055faf6ff4ae4a985fe385e142768 |
| institution | Directory Open Access Journal |
| issn | 1018-3647 |
| language | English |
| last_indexed | 2024-04-24T10:05:26Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of King Saud University: Science |
| spelling | doaj.art-958055faf6ff4ae4a985fe385e1427682024-04-13T04:20:58ZengElsevierJournal of King Saud University: Science1018-36472024-05-01365103158Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongataM. Elangovan0Murali Santhoshkumar1Kumar Selvaraj2Kuppusamy Sathishkumar3Manimaran Kumar4Mukesh Kumar Dharmalingam Jothinathan5Mansour K. Gatasheh6Gajendra Kumar Gaurav7K. Rajesh8PG & Research Department of Chemistry, Indian Arts and Science College, Kondam, Tamil Nadu, IndiaDepartment of Biotechnology, Thiruvalluvar University, Serkkadu, Vellore, Tamil Nadu 632 115, IndiaInstituto de Desarrollo Tecnológico para la Industria Química (INTEC), CONICET, Ruta Nacional 168, Km. 0, Santa Fe 3000, Argentina; Facultad de Ingeniería Química, Universidad Nacional del Litoral (UNL), Santiago del Estero 2829, Santa Fe 3000, ArgentinaCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu 602 105, India; Corresponding authors.Research Center for Applied Microbiology, National Research and Innovation Agency (BRIN), Cibinong 16911, IndonesiaCenter for Global Health Research, Saveetha Medical College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai, Tamil Nadu 602 105, IndiaDepartment of Biochemistry, College of Science, King Saud University, P.O Box 2455, Riyadh 11451, Saudi ArabiaSchools of Physics and Electronic Information, Yan’an University, Yan’an 716000, ChinaPG & Research Department of Chemistry, Arignar Anna Govt. Arts College, Cheyyar, Tamil Nadu, India; Corresponding authors.The current study uses an economical and eco friendly method to produce gold (Au) nanoparticles (NPs) using Polygala elongata leaf (PEL) extract as a reducing and stabilizing agent. The synthesized materials were characterized using a range of methods, including as BET analysis, TEM-SAED, FT-IR, UV–Vis, and XRD. Biogenic AuNPs' spherical form was shown by SEM and TEM investigations, which also showed that the particles' size range was 10–20 nm, their distribution was homogeneous, and there observed minimal aggregation. The production of biogenic AuNPs was confirmed by the observation of a surface plasmon resonance peak in the absorption spectra, which was detected at 540 nm. Additionally, studies were conducted on the catalytic, cytotoxic, antioxidant, and anticancer characteristics of biogenic AuNPs. The biogenic AuNPs exhibited adaptable applications as a heterogeneous catalyst, achieving percentage degradations of 73 % and 88 % under UV light irradiation, particularly in catalyzing the reduction of Methylene Blue (MeB). Furthermore, the antioxidant properties were evaluated using DPPH free radical scavenging assay in regarding rutin, a widely used antioxidant. With a cytotoxicity value of 500 µg/ml, the produced AuNPs had a strong dose-dependent inhibitory effect on the development of the lung cancer cell line (A549). Therefore, biogenic AuNPs hold potential applications across various research domains, spanning biological and industrial sectors, as well as in the removal of harmful contaminants in water purification.http://www.sciencedirect.com/science/article/pii/S1018364724000703AuNPsPEL extractUltrasonicAntioxidantCytotoxicityPhoto catalytic |
| spellingShingle | M. Elangovan Murali Santhoshkumar Kumar Selvaraj Kuppusamy Sathishkumar Manimaran Kumar Mukesh Kumar Dharmalingam Jothinathan Mansour K. Gatasheh Gajendra Kumar Gaurav K. Rajesh Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata Journal of King Saud University: Science AuNPs PEL extract Ultrasonic Antioxidant Cytotoxicity Photo catalytic |
| title | Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata |
| title_full | Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata |
| title_fullStr | Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata |
| title_full_unstemmed | Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata |
| title_short | Sunlight-driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles (AuNPs) employing Polygala elongata |
| title_sort | sunlight driven photocatalytic and anticancer properties of biogenic synthesized gold nanoparticles aunps employing polygala elongata |
| topic | AuNPs PEL extract Ultrasonic Antioxidant Cytotoxicity Photo catalytic |
| url | http://www.sciencedirect.com/science/article/pii/S1018364724000703 |
| work_keys_str_mv | AT melangovan sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT muralisanthoshkumar sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT kumarselvaraj sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT kuppusamysathishkumar sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT manimarankumar sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT mukeshkumardharmalingamjothinathan sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT mansourkgatasheh sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT gajendrakumargaurav sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata AT krajesh sunlightdrivenphotocatalyticandanticancerpropertiesofbiogenicsynthesizedgoldnanoparticlesaunpsemployingpolygalaelongata |