Generation of Fad2 and Fad3 transgenic mice that produce n-6 and n-3 polyunsaturated fatty acids

Generation of Fad2 and Fad3 transgenic mice that produce n-6 and n-3 polyunsaturated fatty acids

Linoleic acid (18 : 2, n-6) and α-linolenic acid (18 : 3, n-3) are polyunsaturated fatty acids (PUFAs), which are essential for mammalian health, development and growth. However, the majority of mammals, including humans, are incapable of synthesizing n-6 and n-3 PUFAs. Mammals must obtain n-6 and n...

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Bibliographic Details
Main Authors: Lishuang Song, Lei Yang, Jiapeng Wang, Xuefei Liu, Lige Bai, Anqi Di, Guangpeng Li
Format: Article
Language:English
Published: The Royal Society 2019-10-01
Series:Open Biology
Subjects:
polyunsaturated fatty acids (pufas)
n-3/6 pufas
fatty acid desaturase (fad)
fad2/3
transgenic mice
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.190140

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