Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review

Introduction Nowadays, most rectal tumours are treated open or minimally invasive, using laparoscopic, robot-assisted or transanal total mesorectal excision. However, insight into the total costs of these techniques is limited. Since all three techniques are currently being performed, including cost...

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Main Authors: Maarten Postma, Roel Hompes, Klaas Havenga, Esther C J Consten, Ritchie T J Geitenbeek, Thijs A Burghgraef, Mark Broekman, Bram P A Schop, Tom G F Lieverse
Format: Article
Language:English
Published: BMJ Publishing Group 2022-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/8/e057803.full
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author Maarten Postma
Roel Hompes
Klaas Havenga
Esther C J Consten
Ritchie T J Geitenbeek
Thijs A Burghgraef
Mark Broekman
Bram P A Schop
Tom G F Lieverse
author_facet Maarten Postma
Roel Hompes
Klaas Havenga
Esther C J Consten
Ritchie T J Geitenbeek
Thijs A Burghgraef
Mark Broekman
Bram P A Schop
Tom G F Lieverse
author_sort Maarten Postma
collection DOAJ
description Introduction Nowadays, most rectal tumours are treated open or minimally invasive, using laparoscopic, robot-assisted or transanal total mesorectal excision. However, insight into the total costs of these techniques is limited. Since all three techniques are currently being performed, including cost considerations in the choice of treatment technique may significantly impact future healthcare costs. Therefore, this systematic review aims to provide an overview of evidence regarding costs in patients with rectal cancer following open, laparoscopic, robot-assisted and transanal total mesorectal excision.Methods and analysis A systematic search will be conducted for papers between January 2000 and March 2022. Databases PubMed/MEDLINE, EMBASE, Scopus, Web of Science and Cochrane Library databases will be searched. Study selection, data extraction and quality assessment will be performed independently by four reviewers and discrepancies will be resolved through discussion. The Consensus Health Economic Criteria list will be used for assessing risk of bias. Total costs of the different techniques, consisting of but not limited to, theatre, in-hospital and postoperative costs, will be the primary outcome.Ethics and dissemination No ethical approval is required, as there is no collection of patient data at an individual level. Findings will be disseminated widely, through peer-reviewed publication and presentation at relevant national and international conferences.Trial registration number CRD42021261125.
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spelling doaj.art-95815b15461b43b4b0cb93cfba50d1432022-12-22T03:06:50ZengBMJ Publishing GroupBMJ Open2044-60552022-08-0112810.1136/bmjopen-2021-057803Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic reviewMaarten Postma0Roel Hompes1Klaas Havenga2Esther C J Consten3Ritchie T J Geitenbeek4Thijs A Burghgraef5Mark Broekman6Bram P A Schop7Tom G F Lieverse8Unit of Global Health, Department of Health Sciences, University of Groningen, University Medical Center, Groningen, The NetherlandsSurgery, Amsterdam UMC,University of Amsterdam, Amsterdam, The Netherlands2 Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands4 Surgery, Meander Medical Centre, Amersfoort, the NetherlandsDepartment of Surgery, Meander MC, Amersfoort, The NetherlandsDepartment of Surgery, Meander MC, Amersfoort, The NetherlandsDepartment of Surgery, University Medical Centre Groningen, Groningen, The NetherlandsDepartment of Surgery, University Medical Centre Groningen, Groningen, The NetherlandsDepartment of Surgery, University Medical Centre Groningen, Groningen, The NetherlandsIntroduction Nowadays, most rectal tumours are treated open or minimally invasive, using laparoscopic, robot-assisted or transanal total mesorectal excision. However, insight into the total costs of these techniques is limited. Since all three techniques are currently being performed, including cost considerations in the choice of treatment technique may significantly impact future healthcare costs. Therefore, this systematic review aims to provide an overview of evidence regarding costs in patients with rectal cancer following open, laparoscopic, robot-assisted and transanal total mesorectal excision.Methods and analysis A systematic search will be conducted for papers between January 2000 and March 2022. Databases PubMed/MEDLINE, EMBASE, Scopus, Web of Science and Cochrane Library databases will be searched. Study selection, data extraction and quality assessment will be performed independently by four reviewers and discrepancies will be resolved through discussion. The Consensus Health Economic Criteria list will be used for assessing risk of bias. Total costs of the different techniques, consisting of but not limited to, theatre, in-hospital and postoperative costs, will be the primary outcome.Ethics and dissemination No ethical approval is required, as there is no collection of patient data at an individual level. Findings will be disseminated widely, through peer-reviewed publication and presentation at relevant national and international conferences.Trial registration number CRD42021261125.https://bmjopen.bmj.com/content/12/8/e057803.full
spellingShingle Maarten Postma
Roel Hompes
Klaas Havenga
Esther C J Consten
Ritchie T J Geitenbeek
Thijs A Burghgraef
Mark Broekman
Bram P A Schop
Tom G F Lieverse
Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review
BMJ Open
title Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review
title_full Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review
title_fullStr Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review
title_full_unstemmed Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review
title_short Cost analysis and cost-effectiveness of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in patients with rectal cancer: a protocol for a systematic review
title_sort cost analysis and cost effectiveness of open versus laparoscopic versus robot assisted versus transanal total mesorectal excision in patients with rectal cancer a protocol for a systematic review
url https://bmjopen.bmj.com/content/12/8/e057803.full
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