Robot-assisted line bisection in patients with Complex Regional Pain Syndrome.
Complex Regional Pain Syndrome (CRPS) is characterized by pain, motor and inflammatory symptoms usually affecting one limb. Cognitive difficulties have been reported to affect patients' ability to represent, perceive and use their affected limb. It is debated whether these difficulties result f...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2019-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0213732 |
| _version_ | 1819114690207285248 |
|---|---|
| author | Charlotte Verfaille Lieve Filbrich David Cordova Bulens Philippe Lefèvre Anne Berquin Olivier Barbier Xavier Libouton Virginie Fraselle Dominique Mouraux Valéry Legrain |
| author_facet | Charlotte Verfaille Lieve Filbrich David Cordova Bulens Philippe Lefèvre Anne Berquin Olivier Barbier Xavier Libouton Virginie Fraselle Dominique Mouraux Valéry Legrain |
| author_sort | Charlotte Verfaille |
| collection | DOAJ |
| description | Complex Regional Pain Syndrome (CRPS) is characterized by pain, motor and inflammatory symptoms usually affecting one limb. Cognitive difficulties have been reported to affect patients' ability to represent, perceive and use their affected limb. It is debated whether these difficulties result from deficits in controlling goal-directed movements in space or from a learned strategy to protect the affected limb. In order to dissociate the two hypotheses, patients with upper-limb CRPS were asked to move with their unaffected hand towards visual targets projected at different positions on a horizontal semi-reflexive mirror. By means of a robotic handle placed below the screen, they were asked to move a cursor, to reach and cross lines at their estimated midpoint. In some of the stimulation series, the affected hand was placed below the mirror so that some lines appeared projected onto that hand. Vision of the hands and the robotic handle was preserved or prevented by opening or closing a shutter below the mirror. Lines were displayed on the mirror according to which part of the body was affected (ispi- vs. contralateral) and the actual position of the affected hand (inside vs. outside the workspace). Comparatively to control participants, CRPS patients generally biased their estimation by bisecting the lines towards their left side, irrelative of which part of the body was affected and the position of the affected hand, both in ipsi- and contralateral space, with only a few exceptions. Our results are in line with previous studies having described a visuospatial deficit in CRPS patients and discard the explanation of observed symptoms in terms of learned nonuse strategies, as only the unaffected hand was used to perform the task. It is suggested that CRPS patients can display difficulties to perform tasks requesting visuo-motor coordination, reflecting the complex cortical reorganization occurring in CRPS. |
| first_indexed | 2024-12-22T04:49:18Z |
| format | Article |
| id | doaj.art-9584c59e07c14cc286afe092f3a20e41 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-22T04:49:18Z |
| publishDate | 2019-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-9584c59e07c14cc286afe092f3a20e412022-12-21T18:38:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032019-01-01145e021373210.1371/journal.pone.0213732Robot-assisted line bisection in patients with Complex Regional Pain Syndrome.Charlotte VerfailleLieve FilbrichDavid Cordova BulensPhilippe LefèvreAnne BerquinOlivier BarbierXavier LiboutonVirginie FraselleDominique MourauxValéry LegrainComplex Regional Pain Syndrome (CRPS) is characterized by pain, motor and inflammatory symptoms usually affecting one limb. Cognitive difficulties have been reported to affect patients' ability to represent, perceive and use their affected limb. It is debated whether these difficulties result from deficits in controlling goal-directed movements in space or from a learned strategy to protect the affected limb. In order to dissociate the two hypotheses, patients with upper-limb CRPS were asked to move with their unaffected hand towards visual targets projected at different positions on a horizontal semi-reflexive mirror. By means of a robotic handle placed below the screen, they were asked to move a cursor, to reach and cross lines at their estimated midpoint. In some of the stimulation series, the affected hand was placed below the mirror so that some lines appeared projected onto that hand. Vision of the hands and the robotic handle was preserved or prevented by opening or closing a shutter below the mirror. Lines were displayed on the mirror according to which part of the body was affected (ispi- vs. contralateral) and the actual position of the affected hand (inside vs. outside the workspace). Comparatively to control participants, CRPS patients generally biased their estimation by bisecting the lines towards their left side, irrelative of which part of the body was affected and the position of the affected hand, both in ipsi- and contralateral space, with only a few exceptions. Our results are in line with previous studies having described a visuospatial deficit in CRPS patients and discard the explanation of observed symptoms in terms of learned nonuse strategies, as only the unaffected hand was used to perform the task. It is suggested that CRPS patients can display difficulties to perform tasks requesting visuo-motor coordination, reflecting the complex cortical reorganization occurring in CRPS.https://doi.org/10.1371/journal.pone.0213732 |
| spellingShingle | Charlotte Verfaille Lieve Filbrich David Cordova Bulens Philippe Lefèvre Anne Berquin Olivier Barbier Xavier Libouton Virginie Fraselle Dominique Mouraux Valéry Legrain Robot-assisted line bisection in patients with Complex Regional Pain Syndrome. PLoS ONE |
| title | Robot-assisted line bisection in patients with Complex Regional Pain Syndrome. |
| title_full | Robot-assisted line bisection in patients with Complex Regional Pain Syndrome. |
| title_fullStr | Robot-assisted line bisection in patients with Complex Regional Pain Syndrome. |
| title_full_unstemmed | Robot-assisted line bisection in patients with Complex Regional Pain Syndrome. |
| title_short | Robot-assisted line bisection in patients with Complex Regional Pain Syndrome. |
| title_sort | robot assisted line bisection in patients with complex regional pain syndrome |
| url | https://doi.org/10.1371/journal.pone.0213732 |
| work_keys_str_mv | AT charlotteverfaille robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT lievefilbrich robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT davidcordovabulens robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT philippelefevre robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT anneberquin robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT olivierbarbier robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT xavierlibouton robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT virginiefraselle robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT dominiquemouraux robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome AT valerylegrain robotassistedlinebisectioninpatientswithcomplexregionalpainsyndrome |