High glucose and TGF-β1 reduce expression of endoplasmic reticulum-resident selenoprotein S and selenoprotein N in human mesangial cells

High glucose and TGF-β1 reduce expression of endoplasmic reticulum-resident selenoprotein S and selenoprotein N in human mesangial cells

There are seven endoplasmic reticulum (ER)-resident selenoproteins in human body and they can regulate the inflammation, oxidative stress, and ER stress. We established transforming growth factor-β1 (TGF-β1) or high glucose (HG) induced human mesangial cells (HMCs) fibronectin expression model in vi...

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Bibliographic Details
Main Authors: Fumeng Huang, Yuanxu Guo, Li Wang, Lanmei Jing, Zhao Chen, Shemin Lu, Rongguo Fu, Lifang Tian
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Renal Failure
Subjects:
endoplasmic reticulum
selenoprotein s
selenoprotein n
hmcs
glucose
tgf-β1
Online Access:http://dx.doi.org/10.1080/0886022X.2019.1641413

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