Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients
Abstract Objective: Endoscopic resection(ER) is effective therapy on EGC and which is treated according to the histological diagnosis of forcep biopsy. But sometimes the histological diagnosis of forcep biopsy and post-ER does not match with each other and it might lead to wrong treatment. The aim o...
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| Format: | Article |
| Language: | English |
| Published: |
Kosin University College of Medicine
2014-12-01
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| Series: | Kosin Medical Journal |
| Subjects: | |
| Online Access: | http://www.kosinmedj.org/upload/pdf/ksmc029-02-04.pdf |
| _version_ | 1797991497676619776 |
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| author | Joo Seok Kim Sae Hee Kim Min Gyu Kim Ah Jeong Ryu Il Hwan Ryu Jae Jun Lee Jae Woong Jeon Ji Wook Choi Anna Kim |
| author_facet | Joo Seok Kim Sae Hee Kim Min Gyu Kim Ah Jeong Ryu Il Hwan Ryu Jae Jun Lee Jae Woong Jeon Ji Wook Choi Anna Kim |
| author_sort | Joo Seok Kim |
| collection | DOAJ |
| description | Abstract Objective: Endoscopic resection(ER) is effective therapy on EGC and which is treated according to the histological diagnosis of forcep biopsy. But sometimes the histological diagnosis of forcep biopsy and post-ER does not match with each other and it might lead to wrong treatment. The aim of this study is to find the frequency of histologic differences between forcep biopsy and post-ER, and to confirm the characteristics of lesions which make errors. Methods: We selected the confirmed cancer cases of 141 patients of 1359 gastric tumor lesions which were treated under the ER in Eulji university hospital from May 2005 to March 2013. They were sorted by the age and sex of patient, location of lesion, present of ulcer and depression to identify the discordance between forcep biopsy and ER. The discordant group was compared with non-cancer-diagnosed controlled group, retrospectively. Results: 70 cases(5.5%) of 1283 cases of “cancer negative” in forceps biopsy were fo䴸nd to be diagnosed cancer on final diagnosis of cancer by post-ER result. In this discordant group showed characteristics of bigger size that are with more frequently in tumor size D15mm(17.9% vs. 31.4%, p=0.03), have depressed lesion(ᄀ 4.3% vs. 41.4%, p<0.01) and have 䴸lceration(2.4% vs.18.6%, p<0.01) than that of 84 control gro䴸p not diagnosed cancer. Conclusions: In cases of tumor with size D15mm, presented with depressed lesion and ulceration, we should consider combined cancer, even the result of forcep biopsy was negative. Therefore, more careful and accurate resection should be taken with characters listed above. |
| first_indexed | 2024-04-11T08:53:05Z |
| format | Article |
| id | doaj.art-958d5d1a88cd49c8a24df5befd5e1fed |
| institution | Directory Open Access Journal |
| issn | 2005-9531 2586-7024 |
| language | English |
| last_indexed | 2024-04-11T08:53:05Z |
| publishDate | 2014-12-01 |
| publisher | Kosin University College of Medicine |
| record_format | Article |
| series | Kosin Medical Journal |
| spelling | doaj.art-958d5d1a88cd49c8a24df5befd5e1fed2022-12-22T04:33:26ZengKosin University College of MedicineKosin Medical Journal2005-95312586-70242014-12-0129211712410.7180/kmj.2014.29.2.117137Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patientsJoo Seok Kim0Sae Hee Kim1Min Gyu Kim2Ah Jeong Ryu3Il Hwan Ryu4Jae Jun Lee5Jae Woong Jeon6Ji Wook Choi7Anna Kim8Department of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaDepartment of Internal Medicine, Eulji University Hospital, Daejon, KoreaAbstract Objective: Endoscopic resection(ER) is effective therapy on EGC and which is treated according to the histological diagnosis of forcep biopsy. But sometimes the histological diagnosis of forcep biopsy and post-ER does not match with each other and it might lead to wrong treatment. The aim of this study is to find the frequency of histologic differences between forcep biopsy and post-ER, and to confirm the characteristics of lesions which make errors. Methods: We selected the confirmed cancer cases of 141 patients of 1359 gastric tumor lesions which were treated under the ER in Eulji university hospital from May 2005 to March 2013. They were sorted by the age and sex of patient, location of lesion, present of ulcer and depression to identify the discordance between forcep biopsy and ER. The discordant group was compared with non-cancer-diagnosed controlled group, retrospectively. Results: 70 cases(5.5%) of 1283 cases of “cancer negative” in forceps biopsy were fo䴸nd to be diagnosed cancer on final diagnosis of cancer by post-ER result. In this discordant group showed characteristics of bigger size that are with more frequently in tumor size D15mm(17.9% vs. 31.4%, p=0.03), have depressed lesion(ᄀ 4.3% vs. 41.4%, p<0.01) and have 䴸lceration(2.4% vs.18.6%, p<0.01) than that of 84 control gro䴸p not diagnosed cancer. Conclusions: In cases of tumor with size D15mm, presented with depressed lesion and ulceration, we should consider combined cancer, even the result of forcep biopsy was negative. Therefore, more careful and accurate resection should be taken with characters listed above.http://www.kosinmedj.org/upload/pdf/ksmc029-02-04.pdfdifferencesearly gastric cancerendoscopic resectionforcep biopsyhistologic |
| spellingShingle | Joo Seok Kim Sae Hee Kim Min Gyu Kim Ah Jeong Ryu Il Hwan Ryu Jae Jun Lee Jae Woong Jeon Ji Wook Choi Anna Kim Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients Kosin Medical Journal differences early gastric cancer endoscopic resection forcep biopsy histologic |
| title | Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients |
| title_full | Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients |
| title_fullStr | Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients |
| title_full_unstemmed | Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients |
| title_short | Pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients |
| title_sort | pathological differences between forceps biopsy specimens and endoscopic resection specimens in early gastric cancer patients |
| topic | differences early gastric cancer endoscopic resection forcep biopsy histologic |
| url | http://www.kosinmedj.org/upload/pdf/ksmc029-02-04.pdf |
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