Clinacanthus nutans: Its potential against diabetic vascular diseases
Diabetes is an independent risk factor for the development of cardiovascular disease, with approximately 80% of cardiovascular mortality and morbidity linked to vascular complications such as atherosclerosis. It has been estimated that up to one-third of patients with diabetes mellitus use some form...
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| Format: | Article |
| Language: | English |
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Universidade de São Paulo
2021-04-01
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| Series: | Brazilian Journal of Pharmaceutical Sciences |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100635&tlng=en |
| _version_ | 1818337065105883136 |
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| author | Ahmad Khusairi Azemi Siti Safiah Mokhtar Aida Hanum Ghulam Rasool |
| author_facet | Ahmad Khusairi Azemi Siti Safiah Mokhtar Aida Hanum Ghulam Rasool |
| author_sort | Ahmad Khusairi Azemi |
| collection | DOAJ |
| description | Diabetes is an independent risk factor for the development of cardiovascular disease, with approximately 80% of cardiovascular mortality and morbidity linked to vascular complications such as atherosclerosis. It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and/or alternative medicine. One plant that has received attention from diabetic patients for its perceived antidiabetic properties is Clinacanthus nutans, a member of the Acanthaceae family that is known as snake grass. Ethnomedical applications of this herb have been identified for the treatment of certain conditions, including fever, diabetes, skin rashes, and insect bites. This review aims to assess the potential of C. nutans to be used in the prevention and/or treatment of diabetic vasculopathy. Evidence for antidiabetic, anti-inflammatory, and dyslipidemic properties of C. nutans, as shown from experimental studies, is presented and discussed. Diabetes, inflammation, and hyperlipidemia are known to play significant roles in the initiation and severity of diabetic cardiovascular disease; thus, targeting these factors might be beneficial for preventing and/or treating diabetic vasculopathy. |
| first_indexed | 2024-12-13T14:49:17Z |
| format | Article |
| id | doaj.art-959f2ab38ba2485db6f87c51f397be2d |
| institution | Directory Open Access Journal |
| issn | 2175-9790 |
| language | English |
| last_indexed | 2024-12-13T14:49:17Z |
| publishDate | 2021-04-01 |
| publisher | Universidade de São Paulo |
| record_format | Article |
| series | Brazilian Journal of Pharmaceutical Sciences |
| spelling | doaj.art-959f2ab38ba2485db6f87c51f397be2d2022-12-21T23:41:22ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902021-04-015610.1590/s2175-97902020000118838Clinacanthus nutans: Its potential against diabetic vascular diseasesAhmad Khusairi AzemiSiti Safiah Mokhtarhttps://orcid.org/0000-0002-0114-5573Aida Hanum Ghulam RasoolDiabetes is an independent risk factor for the development of cardiovascular disease, with approximately 80% of cardiovascular mortality and morbidity linked to vascular complications such as atherosclerosis. It has been estimated that up to one-third of patients with diabetes mellitus use some form of complementary and/or alternative medicine. One plant that has received attention from diabetic patients for its perceived antidiabetic properties is Clinacanthus nutans, a member of the Acanthaceae family that is known as snake grass. Ethnomedical applications of this herb have been identified for the treatment of certain conditions, including fever, diabetes, skin rashes, and insect bites. This review aims to assess the potential of C. nutans to be used in the prevention and/or treatment of diabetic vasculopathy. Evidence for antidiabetic, anti-inflammatory, and dyslipidemic properties of C. nutans, as shown from experimental studies, is presented and discussed. Diabetes, inflammation, and hyperlipidemia are known to play significant roles in the initiation and severity of diabetic cardiovascular disease; thus, targeting these factors might be beneficial for preventing and/or treating diabetic vasculopathy.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100635&tlng=enC. nutansDiabetesInflammationCardiovascular disease |
| spellingShingle | Ahmad Khusairi Azemi Siti Safiah Mokhtar Aida Hanum Ghulam Rasool Clinacanthus nutans: Its potential against diabetic vascular diseases Brazilian Journal of Pharmaceutical Sciences C. nutans Diabetes Inflammation Cardiovascular disease |
| title | Clinacanthus nutans: Its potential against diabetic vascular diseases |
| title_full | Clinacanthus nutans: Its potential against diabetic vascular diseases |
| title_fullStr | Clinacanthus nutans: Its potential against diabetic vascular diseases |
| title_full_unstemmed | Clinacanthus nutans: Its potential against diabetic vascular diseases |
| title_short | Clinacanthus nutans: Its potential against diabetic vascular diseases |
| title_sort | clinacanthus nutans its potential against diabetic vascular diseases |
| topic | C. nutans Diabetes Inflammation Cardiovascular disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100635&tlng=en |
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