Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy

Purpose: To assess choroidal perfusion before and after orbital decompression surgery in patients with Graves' ophthalmopathy. Methods: In this interventional case series, surgical decompression for optic nerve compromise was performed on four eyes of three patients with Graves' disease. C...

Full description

Bibliographic Details
Main Authors: Narieman Nik, Amelia Fong, Marianna Derdzakyan, Chrysavgi Adamopoulou, Adam Sise, Aziz Khanifar, Reginald Sanders
Format: Article
Language:English
Published: Knowledge E 2017-01-01
Series:Journal of Ophthalmic & Vision Research
Subjects:
Online Access:http://www.jovr.org/article.asp?issn=2008-322X;year=2017;volume=12;issue=2;spage=183;epage=186;aulast=Nik
_version_ 1811249388288212992
author Narieman Nik
Amelia Fong
Marianna Derdzakyan
Chrysavgi Adamopoulou
Adam Sise
Aziz Khanifar
Reginald Sanders
author_facet Narieman Nik
Amelia Fong
Marianna Derdzakyan
Chrysavgi Adamopoulou
Adam Sise
Aziz Khanifar
Reginald Sanders
author_sort Narieman Nik
collection DOAJ
description Purpose: To assess choroidal perfusion before and after orbital decompression surgery in patients with Graves' ophthalmopathy. Methods: In this interventional case series, surgical decompression for optic nerve compromise was performed on four eyes of three patients with Graves' disease. Complete ophthalmic examination including visual acuity, color vision, and intraocular pressure assessment were done pre- and postoperatively. High-speed indocyanine green angiography was performed prior to surgery and was repeated one year after surgery. Results: In all three patients, choroidal perfusion defects were noted pre-operatively in the eyes with the compressive optic neuropathy. At 1 year after orbital decompression surgery, the defects improved or completely resolved. Improved visual acuity and color perception, as well as decreased intraocular pressure, were also noted postoperatively. Conclusion: Patients with Graves' orbitopathy may have abnormal choroidal perfusion even in the absence of optic neuropathy. Orbital decompression may improve choroidal circulation in these patients.
first_indexed 2024-04-12T15:45:39Z
format Article
id doaj.art-95a3508695c24212aca3441c68176028
institution Directory Open Access Journal
issn 2008-322X
language English
last_indexed 2024-04-12T15:45:39Z
publishDate 2017-01-01
publisher Knowledge E
record_format Article
series Journal of Ophthalmic & Vision Research
spelling doaj.art-95a3508695c24212aca3441c681760282022-12-22T03:26:40ZengKnowledge EJournal of Ophthalmic & Vision Research2008-322X2017-01-0112218318610.4103/jovr.jovr_165_16Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathyNarieman NikAmelia FongMarianna DerdzakyanChrysavgi AdamopoulouAdam SiseAziz KhanifarReginald SandersPurpose: To assess choroidal perfusion before and after orbital decompression surgery in patients with Graves' ophthalmopathy. Methods: In this interventional case series, surgical decompression for optic nerve compromise was performed on four eyes of three patients with Graves' disease. Complete ophthalmic examination including visual acuity, color vision, and intraocular pressure assessment were done pre- and postoperatively. High-speed indocyanine green angiography was performed prior to surgery and was repeated one year after surgery. Results: In all three patients, choroidal perfusion defects were noted pre-operatively in the eyes with the compressive optic neuropathy. At 1 year after orbital decompression surgery, the defects improved or completely resolved. Improved visual acuity and color perception, as well as decreased intraocular pressure, were also noted postoperatively. Conclusion: Patients with Graves' orbitopathy may have abnormal choroidal perfusion even in the absence of optic neuropathy. Orbital decompression may improve choroidal circulation in these patients.http://www.jovr.org/article.asp?issn=2008-322X;year=2017;volume=12;issue=2;spage=183;epage=186;aulast=NikChoroid; Circulation; Graves; Indocyanine Green Angiography
spellingShingle Narieman Nik
Amelia Fong
Marianna Derdzakyan
Chrysavgi Adamopoulou
Adam Sise
Aziz Khanifar
Reginald Sanders
Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy
Journal of Ophthalmic & Vision Research
Choroid; Circulation; Graves; Indocyanine Green Angiography
title Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy
title_full Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy
title_fullStr Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy
title_full_unstemmed Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy
title_short Changes in choroidal perfusion after orbital decompression surgery for Graves′ ophthalmopathy
title_sort changes in choroidal perfusion after orbital decompression surgery for graves ophthalmopathy
topic Choroid; Circulation; Graves; Indocyanine Green Angiography
url http://www.jovr.org/article.asp?issn=2008-322X;year=2017;volume=12;issue=2;spage=183;epage=186;aulast=Nik
work_keys_str_mv AT nariemannik changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy
AT ameliafong changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy
AT mariannaderdzakyan changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy
AT chrysavgiadamopoulou changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy
AT adamsise changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy
AT azizkhanifar changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy
AT reginaldsanders changesinchoroidalperfusionafterorbitaldecompressionsurgeryforgravesophthalmopathy