Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report
Laryngeal oedema caused by acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a life-threatening condition. The swelling is bradykinin mediated and will not respond to the usual treatment with antihistamines, corticosteroids, or epinephrine. Instead, kallikrein-bradykinin-targeted th...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2021-05-01
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| Series: | The Journal of Critical Care Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/jccm-2021-0003 |
| _version_ | 1797430410554114048 |
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| author | Bara Noémi-Anna Nadasan Valentin |
| author_facet | Bara Noémi-Anna Nadasan Valentin |
| author_sort | Bara Noémi-Anna |
| collection | DOAJ |
| description | Laryngeal oedema caused by acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a life-threatening condition. The swelling is bradykinin mediated and will not respond to the usual treatment with antihistamines, corticosteroids, or epinephrine. Instead, kallikrein-bradykinin-targeted therapies should be used promptly to prevent asphyxiation. |
| first_indexed | 2024-03-09T09:27:10Z |
| format | Article |
| id | doaj.art-95a41541df0f41f69febebd4bcfb77ce |
| institution | Directory Open Access Journal |
| issn | 2393-1817 |
| language | English |
| last_indexed | 2024-03-09T09:27:10Z |
| publishDate | 2021-05-01 |
| publisher | Sciendo |
| record_format | Article |
| series | The Journal of Critical Care Medicine |
| spelling | doaj.art-95a41541df0f41f69febebd4bcfb77ce2023-12-02T05:47:43ZengSciendoThe Journal of Critical Care Medicine2393-18172021-05-017213614010.2478/jccm-2021-0003Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case ReportBara Noémi-Anna0Nadasan Valentin1Hereditary Angioedema Expertise Centre, Sangeorgiu De Mures, MuresRomaniaGeorge Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, MuresRomaniaLaryngeal oedema caused by acquired angioedema due to C1-inhibitor deficiency (C1-INH-AAE) is a life-threatening condition. The swelling is bradykinin mediated and will not respond to the usual treatment with antihistamines, corticosteroids, or epinephrine. Instead, kallikrein-bradykinin-targeted therapies should be used promptly to prevent asphyxiation.https://doi.org/10.2478/jccm-2021-0003acquired c1-inhibitor deficiencylaryngeal oedemaasphyxiationmonoclonal gammopathy of uncertain significanceemergency care treatment plan |
| spellingShingle | Bara Noémi-Anna Nadasan Valentin Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report The Journal of Critical Care Medicine acquired c1-inhibitor deficiency laryngeal oedema asphyxiation monoclonal gammopathy of uncertain significance emergency care treatment plan |
| title | Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report |
| title_full | Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report |
| title_fullStr | Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report |
| title_full_unstemmed | Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report |
| title_short | Resolution of Laryngeal Oedema in a Patient with Acquired C1-Inhibitor Deficiency. A Case Report |
| title_sort | resolution of laryngeal oedema in a patient with acquired c1 inhibitor deficiency a case report |
| topic | acquired c1-inhibitor deficiency laryngeal oedema asphyxiation monoclonal gammopathy of uncertain significance emergency care treatment plan |
| url | https://doi.org/10.2478/jccm-2021-0003 |
| work_keys_str_mv | AT baranoemianna resolutionoflaryngealoedemainapatientwithacquiredc1inhibitordeficiencyacasereport AT nadasanvalentin resolutionoflaryngealoedemainapatientwithacquiredc1inhibitordeficiencyacasereport |