Late onset of oral chronic GVHD

Chronic graft-versus-host disease is the major late complication following allogeneic hematopoietic stem cell transplantation (HSCT), and the major cause for morbidity and loss of quality of life in HSCT long-term survivors. Oral involvement accounts for around 53% - 70% of bone marrow and peripher...

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Main Authors: Paulo Sérgio da Silva Santos, Fábio Luiz Coracin, Fábio Daumas Nunes, Marina Gallottini Magalhães
Format: Article
Language:English
Published: Associação Brasileira de Transplante de Órgãos 2008-06-01
Series:Brazilian Journal of Transplantation
Subjects:
Online Access:https://bjt.emnuvens.com.br/revista/article/view/303
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author Paulo Sérgio da Silva Santos
Fábio Luiz Coracin
Fábio Daumas Nunes
Marina Gallottini Magalhães
author_facet Paulo Sérgio da Silva Santos
Fábio Luiz Coracin
Fábio Daumas Nunes
Marina Gallottini Magalhães
author_sort Paulo Sérgio da Silva Santos
collection DOAJ
description Chronic graft-versus-host disease is the major late complication following allogeneic hematopoietic stem cell transplantation (HSCT), and the major cause for morbidity and loss of quality of life in HSCT long-term survivors. Oral involvement accounts for around 53% - 70% of bone marrow and peripheral blood stem cell recipients, respectively. We report a case of late onset oral chronic GVHD and discuss the role of the oral health care providers in the early diagnosis and management of this disease. Moreover, oral cGVHD development 4 years after transplantation and coincident with withdrawing immunosuppression is most uncommon and shows the importance of tracking the involvement of the oral cavity after allogeneic transplantation.
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spelling doaj.art-95a500f62630426e93978ef8246546712022-12-22T01:24:16ZengAssociação Brasileira de Transplante de ÓrgãosBrazilian Journal of Transplantation2764-15892008-06-0111310.53855/bjt.v11i3.303Late onset of oral chronic GVHDPaulo Sérgio da Silva Santos0Fábio Luiz Coracin1Fábio Daumas Nunes2Marina Gallottini Magalhães3Departamento de Patologia Bucal da Faculdade de Odontologia da Universidade de São Paulo – São Paulo / SP – Brasil.Departamento de Patologia Bucal da Faculdade de Odontologia da Universidade de São Paulo – São Paulo / SP – Brasil.Departamento de Patologia Bucal da Faculdade de Odontologia da Universidade de São Paulo – São Paulo / SP – Brasil.Departamento de Patologia Bucal da Faculdade de Odontologia da Universidade de São Paulo – São Paulo / SP – Brasil. Chronic graft-versus-host disease is the major late complication following allogeneic hematopoietic stem cell transplantation (HSCT), and the major cause for morbidity and loss of quality of life in HSCT long-term survivors. Oral involvement accounts for around 53% - 70% of bone marrow and peripheral blood stem cell recipients, respectively. We report a case of late onset oral chronic GVHD and discuss the role of the oral health care providers in the early diagnosis and management of this disease. Moreover, oral cGVHD development 4 years after transplantation and coincident with withdrawing immunosuppression is most uncommon and shows the importance of tracking the involvement of the oral cavity after allogeneic transplantation. https://bjt.emnuvens.com.br/revista/article/view/303Graft RejectionMouth DiseasesBone Marrow Transplantation
spellingShingle Paulo Sérgio da Silva Santos
Fábio Luiz Coracin
Fábio Daumas Nunes
Marina Gallottini Magalhães
Late onset of oral chronic GVHD
Brazilian Journal of Transplantation
Graft Rejection
Mouth Diseases
Bone Marrow Transplantation
title Late onset of oral chronic GVHD
title_full Late onset of oral chronic GVHD
title_fullStr Late onset of oral chronic GVHD
title_full_unstemmed Late onset of oral chronic GVHD
title_short Late onset of oral chronic GVHD
title_sort late onset of oral chronic gvhd
topic Graft Rejection
Mouth Diseases
Bone Marrow Transplantation
url https://bjt.emnuvens.com.br/revista/article/view/303
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